anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) Antibodies

May act as a negative regulator of cell growth.. Additionally we are shipping UHRF1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UHRF1 29128 Q96T88
UHRF1 316129 Q7TPK1
UHRF1 18140 Q8VDF2
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Top anti-UHRF1 Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UHRF1 Antibody  Positive Control: Lane 1: 60ug HCT116 lysate Lane 2: 60ug HCT116 lysate + siRNA  Primary Antibody Dilution :  1:1000 Secondary Antibody : Anti rabbit-HRP  Secondry Antibody Dilution :  1:5,000 Submitted by: Chinweike Ukomadu, Brigham and Women's Hospital, Boston WB Suggested Anti-UHRF1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Stomach 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IF, WB Western blot analysis of UHRF1 Antibody (Center) (ABIN652792) in Hela cell line lysates (35 µg/lane). UHRF1 (arrow) was detected using the purified polyclonal antibody. UHRF1 Antibody (Center) (ABIN652792) flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to UHRF1 on HeLa cell (antibody concentration 10 µg/mL). UHRF1 monoclonal antibody (M01), clone 3A11 Western Blot analysis of UHRF1 expression in HeLa NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of UHRF1 expression in MCF-7 whole cell lysates (lane 1) and U2OS whole cell lysates (lane 2). UHRF1 at 90KD was detected using rabbit anti- UHRF1 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Detection of Human NP95//UHRF1 by Western Blot and Immunoprecipitation.  Samples: Whole cell lysate (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified rabbit anti-NP95//UHRF1 antibody ABIN261674 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.  NP95//UHRF1 was also immunoprecipitated by another rabbit anti-NP95//UHRF1 antibody, which recognizes a downstream epitope.   Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B). Immunohistochemistry-Paraffin: UHRF1 Antibody [ABIN2616747] - FFPE section of human lung carcinoma. Antibody: Affinity purified rabbit anti-NP95/UHRF1 used at a dilution of 1:200 (1ug/ml). Detection: DAB 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Mouse Un-conjugated ICC, IF, IP, IHC, WB Uhrf1 antibody (mAb) tested by immunofluorescence. Formaldehyde fixed HeLa cells stained with Uhrf1 antibody at a 0.5 µg/ml dilution. 100 μg Log in to see 1 to 2 Days
$495.83
Details
Human Mouse Un-conjugated FM, WB Western blot analysis of ICBP90 on HeLa lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of ICBP90. 50 μg Log in to see 6 to 8 Days
$154.07
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunoperoxidase of monoclonal antibody to UHRF1 on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 3 ug/ml] UHRF1 monoclonal antibody (M01), clone 3A11 Western Blot analysis of UHRF1 expression in Hela S3 NE . 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details

UHRF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Rat (Rattus)
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Mouse (Murine)
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Top referenced anti-UHRF1 Antibodies

  1. Human Monoclonal UHRF1 Primary Antibody for IF, WB - ABIN393646 : Hervouet, Lalier, Debien, Cheray, Geairon, Rogniaux, Loussouarn, Martin, Vallette, Cartron: Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells. in PLoS ONE 2010 (PubMed)
    Show all 5 references for 393646

  2. Human Monoclonal UHRF1 Primary Antibody for ICC, IF - ABIN2668962 : Hopfner, Mousli, Jeltsch, Voulgaris, Lutz, Marin, Bellocq, Oudet, Bronner: ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIalpha expression. in Cancer research 2000 (PubMed)
    Show all 2 references for 2668962

  3. Human Polyclonal UHRF1 Primary Antibody for ICC, IF - ABIN261674 : Ma, Chen, Guo, Wang, Sowa, Zheng, Hu, Zeng, Guo, Diao, Lan, Harper, Shi, Xu, Shi: M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 2 references for 261674

  4. Human Monoclonal UHRF1 Primary Antibody for IF, ELISA - ABIN565416 : Mistry, Gibson, Yun, Sarras, Tamblyn, McPherson: Interplay between Np95 and Eme1 in the DNA damage response. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for 565416

  5. Human Monoclonal UHRF1 Primary Antibody for FM, WB - ABIN968794 : Hopfner, Mousli, Garnier, Redon, du Manoir, Chatton, Ghyselinck, Oudet, Bronner: Genomic structure and chromosomal mapping of the gene coding for ICBP90, a protein involved in the regulation of the topoisomerase IIalpha gene expression. in Gene 2001 (PubMed)
    Show all 2 references for 968794

  6. Human Polyclonal UHRF1 Primary Antibody for FACS, IF - ABIN652792 : Achour, Fuhrmann, Alhosin, Rondé, Chataigneau, Mousli, Schini-Kerth, Bronner: UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity. in Biochemical and biophysical research communications 2009 (PubMed)

  7. Cow (Bovine) Polyclonal UHRF1 Primary Antibody for WB - ABIN2780898 : Achour, Jacq, Rondé, Alhosin, Charlot, Chataigneau, Jeanblanc, Macaluso, Giordano, Hughes, Schini-Kerth, Bronner: The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression. in Oncogene 2008 (PubMed)

More Antibodies against UHRF1 Interaction Partners

Human Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) interaction partners

  1. UHRF1 gene expression levels correlates with the major pathological characteristics of transitional cell carcinoma samples and with the clinical outcome of those patients. Determination of UHRF1 gene expression could have a potential to be used as a sensitive molecular marker in patients with urinary bladder cancer.

  2. decreased UHRF1 expression is a key initial event in the suppression of DNMT1 (show DNMT1 Antibodies)-mediated DNA methylation (show HELLS Antibodies) and in the consequent induction of senescence via increasing WNT5A (show WNT5A Antibodies) expression

  3. Our results provide insights into the molecular basis of DNMT1 (show DNMT1 Antibodies) dysfunction in hereditary sensory and autonomic neuropathies with dementia and hearing loss patients and emphasize the importance of the TS domain in the regulation of DNA methylation (show HELLS Antibodies) in pluripotent and differentiating cells

  4. results identify UHRF1 as a novel HSP90 (show HSP90 Antibodies) client protein and shed light on the regulation of UHRF1 stability and function.

  5. Down-regulation of UHRF1 by RNAi inhibited proliferation and clonogenic ability of medullobastoma cell lines with cell cycle arrest in G1/G2-phase. Cells transfected with lenti-shUHRF1 showed increased p16 (show CDKN2A Antibodies) expression and location shift of CDK4 (show CDK4 Antibodies) in medulloblastoma cells.

  6. Our study uncovered that UHRF1 overexpressed in cervical squamous cell carcinoma and silent UHRF1 gene can reduce tumorigenicity of the CaSki cells by decreasing its proliferation capacity and making it stagnate at G0 and G1 phases as well as accelerating its apoptosis

  7. The overexpression of UHRF1 was correlated with the stage and grade of gastric cancer and is associated with the genotype distribution of MiR (show MLXIP Antibodies)-146a rs2910164.

  8. Studies indicate that ubiquitin like with PHD and ring finger domains 1 protein (UHRF1) interacts with DNA interstrand crosslinks (ICLs) both in vitro and in vivo.

  9. Results showed that UHRF1 was overexpressed in almost all of the prostate cancer cell (PCa (show FLVCR1 Antibodies)) lines. Its expression levels were correlated with some clinical features of PCa (show FLVCR1 Antibodies) suggesting it as an independent prognostic factor for biochemical recurrence.

  10. UHRF1 promotes osteosarcoma cell invasion by downregulating the expression of Ecadherin and increasing epithelialtomesenchymal transition in an Rb1dependent manner.

Pig (Porcine) Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) interaction partners

  1. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1 (show DNMT1 Antibodies), Dnmt3a (show DNMT3A Antibodies), Hdac1 (show HDAC1 Antibodies), Kdm3a (show KDM3A Antibodies) and Uhrf1 were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

Zebrafish Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) interaction partners

  1. Dnmt1 (show DNMT1 Antibodies) stability requires UHRF1 phosphorylation and that crosstalk between the proteins is essential for the function of these two important epigenetic regulators during gastrulation

  2. DNA hypomethylation is the mechanism underlying the cell cycle block and small liver phenotype caused by uhrf1 depletion.

  3. an essential role for UHRF1 phosphorylation by cyclin-dependent kinase 2 (show CDK2 Antibodies)/cyclin A2 (show CCNA2 Antibodies) during early vertebrate development

  4. These data provide the first evidence that Uhrf1 and Dnmt1 (show DNMT1 Antibodies) function is required for vertebrate lens development and maintenance.

  5. uhrf1 is required for physiologic liver growth in both embryos and adults

Mouse (Murine) Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) interaction partners

  1. SETDB1 (show SETDB1 Antibodies) maintains silencing of intracisternal A particle, but in the absence of DNMT1 (show DNMT1 Antibodies), prolonged binding of NP95 to hemimethylated DNA transiently disrupts SETDB1 (show SETDB1 Antibodies)-dependent H3K9me3 deposition.

  2. deletion of Uhrf1 lead to global DNA hypomethylation with a strong activation of the intracisternal A particle (IAP (show ALPI Antibodies)) family of endogenous retroviral elements, accompanied by an increase in 5-hydroxymethylcytosine

  3. Our results provide insights into the molecular basis of DNMT1 (show DNMT1 Antibodies) dysfunction in hereditary sensory and autonomic neuropathies with dementia and hearing loss patients and emphasize the importance of the TS domain in the regulation of DNA methylation (show HELLS Antibodies) in pluripotent and differentiating cells

  4. results identify UHRF1 as a novel HSP90 (show HSP90 Antibodies) client protein and shed light on the regulation of UHRF1 stability and function.

  5. Uhrf1 regulation of the Akt (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) signaling pathway is required for invariant natural killer T cell development.

  6. Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its H3 histone (show HIST1H3B Antibodies) recognition.

  7. the histone modification status at the DMRs of imprinted genes may dictate whether DNA methylation (show HELLS Antibodies) could be restored upon UHRF1 re-expression

  8. UHRF1 is strongly up-regulated during liver regeneration independently of BIRC5 (show BIRC5 Antibodies).

  9. report identifies PARP1 (show PARP1 Antibodies) as a novel modulator of two UHRF1-regulated heterochromatin-associated events: the accumulation of H4K20me3 and the clearance of DNMT1 (show DNMT1 Antibodies)

  10. Uhrf1 deficiency resulted in derepression of the gene (Cdkn1a (show CDKN1A Antibodies)) that encodes the cyclin-dependent kinase (show CDK1 Antibodies) inhibitor p21 (show D4S234E Antibodies) due to hypomethylation of its promoter region, which resulted in cell-cycle arrest of Treg cells.

UHRF1 Antigen Profile

Protein Summary

May act as a negative regulator of cell growth.

Gene names and symbols associated with UHRF1

  • ubiquitin-like with PHD and ring finger domains 1 (UHRF1) antibody
  • ubiquitin-like with PHD and ring finger domains 1 (Uhrf1) antibody
  • ubiquitin-like, containing PHD and RING finger domains, 1 (uhrf1) antibody
  • ubiquitin-like, containing PHD and RING finger domains, 1 (Uhrf1) antibody
  • UHRF1 binding protein 1 (UHRF1BP1) antibody
  • AL022808 antibody
  • C6orf107 antibody
  • dJ349A12.1 antibody
  • fb97f09 antibody
  • hNP95 antibody
  • hUHRF1 antibody
  • ICBP90 antibody
  • NP95 antibody
  • RNF106 antibody
  • UHRF1 antibody
  • wu:fb97f09 antibody
  • zgc:63539 antibody

Protein level used designations for UHRF1

ubiquitin-like, containing PHD and RING finger domains, 1 , ubiquitin-like with PHD and ring finger domains 1 , E3 ubiquitin-protein ligase UHRF1 , RING finger protein 106 , huNp95 , inverted CCAAT box-binding protein of 90 kDa , nuclear protein 95 , nuclear zinc finger protein Np95 , transcription factor ICBP90 , ubiquitin-like PHD and RING finger domain-containing protein 1 , ubiquitin-like-containing PHD and RING finger domains protein 1 , liver regeneration-related protein LRRG126 , mUhrf1 , ICBP90 binding protein 1 , ICBP90-binding protein 1 , UHRF1 (ICBP90) binding protein 1 , UHRF1-binding protein 1 , ubiquitin-like containing PHD and RING finger domains 1-binding protein 1

GENE ID SPECIES
100062347 Equus caballus
455613 Pan troglodytes
29128 Homo sapiens
530411 Bos taurus
316129 Rattus norvegicus
420154 Gallus gallus
611463 Canis lupus familiaris
100511003 Sus scrofa
100719542 Cavia porcellus
406350 Danio rerio
18140 Mus musculus
54887 Homo sapiens
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