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anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) Antibodies

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Additionally we are shipping GABRA2 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GABRA2 2555 P47869
GABRA2 289606  
GABRA2 14395 P26048
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Top anti-GABRA2 Antibodies at antibodies-online.com

Showing 10 out of 83 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of GABRA2 Antibody (C-term) (ABIN653245) in NCI-H460, MDA-MB435 cell line lysates (35 µg/lane). GABRA2 (arrow) was detected using the purified polyclonal antibody. GABRA2 Antibody (C-term) (ABIN653245) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GABRA2 Antibody Titration: 1.25ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti GABRA2/GABA A Receptor alpha 2 Polyclonal Antibody, Unconjugated (ABIN1387528) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Mouse Mouse HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Mouse Mouse FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Mouse Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Mouse Mouse Biotin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details

GABRA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GABRA2 Antibodies

  1. Cow (Bovine) Polyclonal GABRA2 Primary Antibody for WB - ABIN2792259 : Hadingham, Wingrove, Le Bourdelles, Palmer, Ragan, Whiting: Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric ac in Molecular pharmacology 1993 (PubMed)
    Show all 3 references for ABIN2792259

  2. Human Polyclonal GABRA2 Primary Antibody for FACS, IHC (p) - ABIN653245 : Dixon, Morris, Breen, Desrivieres, Jugurnauth, Steiner, Vallada, Guindalini, Laranjeira, Messas, Rosahl, Atack, Peden, Belelli, Lambert, King, Schumann, Stephens: Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

More Antibodies against GABRA2 Interaction Partners

Rhesus Monkey gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) interaction partners

  1. the developmental shift in GABA(A) receptor alpha subunit (show POLG Antibodies) expression continues through adolescence in primate dorsolateral prefrontal cortex

Human gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) interaction partners

  1. A GABRA2 x Parental Monitoring effect on externalizing behavior trajectory was observed, such that A-carriers were largely unaffected by parental monitoring, whereas trajectory for those with the GG genotype was affected by parental monitoring.

  2. GABRA2 SNPs directly predicted adolescent alcohol problems.

  3. Alcohol dependence-associated variation in GABRA2 is associated with differential expression of the entire cluster of GABAA (show GABRg1 Antibodies) subunit genes on chromosome 4p12 in neural stem cells.

  4. Recent drinking history (p = 0.01), and recent drinking history x genotype interaction (p = 0.01) were significantly associated with acute adaptation of the subjective responses to alcohol for the GABRA2 SNP rs279858.

  5. The results of this study support a growing body of evidence linking GABAA (show GABRg1 Antibodies) receptors with the development of alcohol tolerance, dependence and withdrawal symptoms

  6. GABRA2 is significantly associated with rule breaking in mid- to late adolescence, but not substance abuse symptomatology across adolescence.

  7. GABRA2 genetic variants play a role in antipsychotic-associated weight gain.

  8. The results suggest that SNP variation in the GABRA2 gene leads to higer risk of increased drunkenness in the period adolescence to you adulthood

  9. Results suggest that the genetic effect of GABRA2 on externalizing behavior, more specifically on rule breaking is, at least in part, due to its effect on susceptibility to environmental exposure (i.e., peer delinquency)

  10. This study demonstrates an impact of GABRA2 genotype on incentive-motivation neurocircuitry in adolescence, with implications for vulnerability to alcoholism.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) interaction partners

  1. Wild-type and mutant mice have similar baseline nociceptive sensitivities and develop similar hyperalgesia specifically targeting alpha2-GABAA (show GABRg1 Antibodies) receptors which exert their antihyperalgesic effect through enhanced spinal nociceptive control.

  2. GABRA2 subunit expression in hippocampus modulates neurogenesis through nuclear factor of activated T cell (show NFATC3 Antibodies) (NFATc)4 (show NFATC4 Antibodies) activity.

  3. Disrupting the clustering of GABAA (show GABRg1 Antibodies) receptor alpha2 subunits in the frontal cortex leads to reduced gamma-power and cognitive deficits.

  4. Recovery of function following alcoholic intoxication is regulated by Gabra2 and Gabra3 (show GABRA3 Antibodies) receptor subunits.

  5. These findings suggest that alpha2-containing GABA(A) receptors expressed in the CA3 (show CA3 Antibodies) region provide the inhibition that controls hippocampal rhythm during cholinergically induced oscillations

  6. The results of this study emphasize the critical role of GABAergic synaptic signaling for structural maturation of adult-born GCs (show UGCG Antibodies) and formation of glutamatergic synapses.

  7. Data suggest that the availability of distinct GABA(A) R subtypes (Gabra2, -4, and Gabrd) provides a molecular mechanism endowing spatiotemporal specificity to GABAergic control of neuronal maturation in adult brain.

  8. presynaptic GABAA (show GABRg1 Antibodies) receptors residing on the axons or terminals of primary nociceptors play a significant role in spinal pain control.

  9. Arc and Fos, increased about 250% in the alpha2 mutants, Behavioral effects (loss of righting reflex, rotarod) of flurazepam and pentobarbital were not different between alpha2 mutants and wild-type, but they were enhanced for alpha1 knock-in mice.

  10. results show that alpha 2-containing GABAA (show GABRg1 Antibodies) receptors represent a specific molecular substrate that can regulate depressive-like states.

GABRA2 Antigen Profile

Protein Summary

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with GABRA2

  • gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2) antibody
  • gamma-aminobutyric acid (GABA) A receptor, alpha 2 (gabra2) antibody
  • gamma-aminobutyric acid (GABA) A receptor, alpha 2 (Gabra2) antibody
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 (Gabra2) antibody
  • C630048P16Rik antibody
  • Gabra-2 antibody

Protein level used designations for GABRA2

GABA(A) receptor subunit alpha-2 , gamma-aminobutyric acid receptor subunit alpha-2 , GABA-A receptor alpha-1 subunit , gamma-aminobutyric acid (GABA) A receptor, alpha 2 , gamma-aminobutyric acid A receptor alpha 2 , gamma-aminobutyric acid A receptor, alpha 2 precursor-like , GABA(A) receptor, alpha 2 , gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2 , gamma-aminobutyric acid receptor A2 subunit , gamma-aminobutyric acid A receptor, alpha 2

GENE ID SPECIES
703894 Macaca mulatta
751992 Taeniopygia guttata
770511 Gallus gallus
100173835 Pongo abelii
100061914 Equus caballus
100170583 Xenopus (Silurana) tropicalis
100286789 Felis catus
100339376 Oryctolagus cuniculus
100546188 Meleagris gallopavo
2555 Homo sapiens
289606 Rattus norvegicus
447255 Xenopus laevis
482131 Canis lupus familiaris
282236 Bos taurus
461355 Pan troglodytes
14395 Mus musculus
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