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anti-phosphodiesterase 8B (PDE8B) Antibodies

The protein encoded by PDE8B is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDE8B 8622 O95263
PDE8B 218461  
PDE8B 309962  
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Top anti-PDE8B Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated WB PDE8B Antibody (Center) (ABIN1881646) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the PDE8B antibody detected the PDE8B protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Bat Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Gibbon Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated IP, WB Western Blot of PDE8B using rat testis and heart membranes. Antibody (ABIN152797) dilution 1:500. Molecular weight marker positions are marked on the left. 0.1 mg Log in to see 5 to 7 Days
$530.25
Details
Mouse Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Mouse Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details

PDE8B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,


Mouse (Murine)


, , , , ,
Rat (Rattus)


Top referenced anti-PDE8B Antibodies

  1. Mouse (Murine) Polyclonal PDE8B Primary Antibody for WB - ABIN1881646 : Horvath, Faucz, Finkielstain, Nikita, Rothenbuhler, Almeida, Mericq, Stratakis: Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels. in Thyroid : official journal of the American Thyroid Association 2010 (PubMed)
    Show all 3 references for ABIN1881646

More Antibodies against PDE8B Interaction Partners

Human phosphodiesterase 8B (PDE8B) interaction partners

  1. Genetic variation of the PDE8B gene may be involved in the etiology of subclinical hypothyroidism in pregnant women.

  2. A prevalence of the minor allele of PDE8B gene polymorphism associated with elevated serum levels of TSH was demonstrated in patients affected by sporadic nonautoimmune subclinical hypothyroidism.

  3. rs4704397 in phosphodiesterase 8B is associated with thyrotropin and thyroid hormone (show PTH Antibodies) concentrations

  4. There is an association between homozygous A/A as well as homozygous G/G carriers of SNP rs 4704397 in PDE8B and recurrent miscarriage.

  5. PDE8B gene polymorphisms may be correlated with hyperthyroxinemia in the Chinese Han population.

  6. PDE8B is another PDE (show ALDH7A1 Antibodies) gene in which variations may contribute to predisposition of adrenocortical tumours.

  7. In obese children, PDE8B is associated with TSH; the interaction between adiposity and PDE8B on TSH is not synergistic, but follows an additive model.

  8. Common genetic variation in PDE8B is associated with reciprocal changes in thyroid hormone (show PTH Antibodies) levels.

  9. Our analysis revealed separate segregation of an inactivating PDE8B allele from the high-TSH-allele and showed low TSH levels in persons who carry an inactivating PDE8B allele. These data suggest that PDE8B may be involved in regulation of TSH levels.

  10. phosphodiesterase 8B has a role in autosomal-dominant striatal degeneration

Mouse (Murine) phosphodiesterase 8B (PDE8B) interaction partners

  1. Pde8b knockout mice demonstrate improvement in select behaviors, motor-coordination, attenuation of age-induced motor coordination decline and increased anxiety levels.

  2. findings suggest that both PDE8A (show PDE8A Antibodies) and PDE8B play essential roles to maintain low cAMP levels, thereby suppressing resting steroidogenesis by keeping CEH (show EPHX2 Antibodies)/HSL (show LIPE Antibodies) inactive and StAR protein expression low

  3. Phosphodiesterase 8B is a major regulator of pools of cyclic AMP (show TMPRSS5 Antibodies) that promote steroidogenesis.

PDE8B Antigen Profile

Protein Summary

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PDE8B

  • phosphodiesterase 8B (PDE8B) antibody
  • phosphodiesterase 8B (pde8b) antibody
  • phosphodiesterase 8B (Pde8b) antibody
  • ADSD antibody
  • B230331L10Rik antibody
  • C030047E14Rik antibody
  • PDE8B antibody
  • PPNAD3 antibody
  • RNPDE8B antibody

Protein level used designations for PDE8B

phosphodiesterase 8B , high-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B , high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like , 3',5' cyclic nucleotide phosphodiesterase 8B , cell proliferation-inducing gene 22 protein , high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B , hsPDE8B , cAMP-specific cyclic nucleotide phosphodiesterase PDE8

GENE ID SPECIES
427645 Gallus gallus
461796 Pan troglodytes
488939 Canis lupus familiaris
539768 Bos taurus
100020085 Monodelphis domestica
100073273 Equus caballus
100386134 Callithrix jacchus
100449849 Pongo abelii
100468338 Ailuropoda melanoleuca
100490787 Xenopus (Silurana) tropicalis
100522306 Sus scrofa
100542722 Meleagris gallopavo
100565292 Anolis carolinensis
100581907 Nomascus leucogenys
8622 Homo sapiens
218461 Mus musculus
309962 Rattus norvegicus
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