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HLA-DR antibody

HLA-DR Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey, Dog FACS, Func Host: Mouse Monoclonal G46-6 (L243) unconjugated
Catalog No. ABIN1177349
  • Target See all HLA-DR products
    HLA-DR
    Reactivity
    • 117
    • 21
    • 18
    • 17
    • 17
    • 14
    • 11
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    Human, Baboon, Cynomolgus, Rhesus Monkey, Dog
    Host
    • 99
    • 12
    • 9
    Mouse
    Clonality
    • 114
    • 5
    Monoclonal
    Conjugate
    • 39
    • 15
    • 15
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-DR antibody is un-conjugated
    Application
    • 103
    • 32
    • 24
    • 18
    • 17
    • 10
    • 9
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Brand
    BD Pharmingen™
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    Clone
    G46-6 (L243)
    Isotype
    IgG2a kappa
  • Application Notes
    This antibody was tested during development for the mixed lymphocyte reaction (MLR). This antibody fixes complement and is able to block mixed lymphocyte reactions at an antibody concentration of 5 µl/ml.This NA/LE™ format is useful for in vitro functional studies.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Target
    HLA-DR
    Alternative Name
    HLA-DR (HLA-DR Products)
    Background
    Reacts with HLA-DR, a human class II antigen II of the major histocompatibility complex (MHC). HLA-DR is a transmembrane glycoprotein composed of an alpha chain (36 kD) and a beta subunit (27 kD) expressed primarily on antigen presenting cells: B cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in cellular interaction during antigen presentation. This antibody is routinely tested by flow cytometric analysis.
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