Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibody

Details for Product No. ABIN184566
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Antigen
Synonyms
socs3, fj09e12, zgc:56537, wu:fj09e12, MGC64393, MGC75749, xsocs3, MGC81248, atod4, cis3, cish3, socs-3, ssi-3, ssi3, SOCS3, ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3, Cis3, EF-10, Ef10, Ssi3, Socs-3, S ... show more
socs3, fj09e12, zgc:56537, wu:fj09e12, MGC64393, MGC75749, xsocs3, MGC81248, atod4, cis3, cish3, socs-3, ssi-3, ssi3, SOCS3, ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3, Cis3, EF-10, Ef10, Ssi3, Socs-3, Ssi-3 show less
Epitope
C-Term
(14), (11), (7), (6), (3), (3), (1), (1), (1), (1), (1)
Reactivity
Human
(110), (38), (30), (15), (14), (14), (12), (1)
Host
Goat
(64), (57), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(96), (39), (31), (30), (24), (16), (10), (6), (5), (4), (2)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN184566
374.27 $
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Immunogen Peptide with sequence C-PIREFLDQYDAPL, from the C Terminus of the protein sequence according to NP_003946.3.
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name SOCS3
Background Synonyms: SOCS3, CIS3, Cish3, SSI-3, SOCS-3, suppressor of cytokine signaling 3, STAT induced STAT inhibitor 3, cytokine-induced SH2 protein 3, ATOD4, MGC71791, SSI3
Gene ID 9021, 12702, 89829
NCBI Accession NP_003946
Research Area Cancer, Hematopoietic Progenitors, Innate Immunity, Cytokines, Signaling
Application Notes ELISA: antibody detection limit dilution 1:16000.
Western blot: Approx 24 kDa band seen in MOLT-4 lysate. Recommended for use at 4-6 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibody ABIN184566 staining (5µg/ml) of MOLT-4 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
General Roberts, Robb, Rakar et al.: "Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 9324-9, 2001 (PubMed).

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