anti-PAK1 antibody (P21-Activated Kinase 1) (Internal Region)

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Antigen
Synonyms X-PAK1, XPak1, pak, pak-1, pakalpha, PAKalpha, AW045634, PAK-1, Paka
Alternatives
Epitope
Internal Region
(60), (29), (27), (18), (14), (14), (11), (11), (11), (11), (9), (6), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(347), (170), (167), (4), (4), (1), (1)
Host
Goat
(317), (17), (15), (1)
Clonality
Polyclonal
Conjugate
This PAK1 antibody is un-conjugated
(11), (11), (11), (7), (7), (7), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(250), (143), (139), (65), (65), (44), (26), (22), (18), (7), (6), (4), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Peptide with sequence C-NTEKQKKKPKMSDE, from the internal region of the protein sequence according to NP_002567.3.
Blocking Peptide Blocking peptide for this product available: P21-Activated Kinase 1 (PAK1) peptide (ABIN369515)
Cross-Reactivity Dog (Canine)
Cross-Reactivity (Details) No cross-reactivity exptected with PAK3
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name PAK1 (PAK1 Antibody Abstract)
Background Synonyms: PAK1, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), MGC130000, MGC130001, PAKalpha, p21-activated kinase 1, p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
Gene ID 5058, 18479, 29431
NCBI Accession NP_002567
Research Area Cancer, Apoptosis/Necrosis, Kinases/Phosphatases
Pathways MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes ELISA: antibody detection limit dilution 1:4000.
Western blot: Approx 70 kDa band observed in Human, Mouse and Rat Brain lysates (calculated MW of 60.6 kDa according to NP_002567.3). Recommended concentration: 1-3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
Image no. 1 for anti-PAK1 antibody (P21-Activated Kinase 1) (Internal Region) (ABIN185685) ABIN185685 (1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Prima...
Background publications Zhao, Ma, Calon et al.: "Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease." in: Nature neuroscience, Vol. 9, Issue 2, pp. 234-42, 2006 (PubMed).

Catalog No. ABIN185685
$221.76
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