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NFKB1 antibody
NFKB1
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NFKB1 Antibody
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Target
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NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Reactivity
All reactivities for NFKB1 antibodies
Human
Host
All hosts for NFKB1 antibodies
Rabbit
Clonality
All clonalities for NFKB1 antibodies
Polyclonal
Conjugate
All conjugates for NFKB1 antibodies
This NFKB1 antibody is un-conjugated
Application
All applications for NFKB1 antibodies
Western Blotting (WB), ELISA
Purification
Affinity purification
Immunogen
Recombinant protein of human NFKB1
Isotype
IgG
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Discover our top product NFKB1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:200-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.1 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Handling Advice
Avoid freeze / thaw cycles.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NFKB1
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Target
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Alternative Name
NFkappaB-p105/p50 (NFKB1 Products )
Synonyms
GKLP antibody, NKTL antibody, NTKL antibody, P105 antibody, TAPK antibody, TEIF antibody, TRAP antibody, EBP-1 antibody, KBF1 antibody, NF-kB1 antibody, NF-kappa-B antibody, NF-kappaB antibody, NFKB-p105 antibody, NFKB-p50 antibody, NFkappaB antibody, p105 antibody, p50 antibody, NF-kB antibody, NF-KB1 antibody, ebp-1 antibody, kbf1 antibody, nf-kappa-b antibody, nf-kappaB antibody, nfkb-p105 antibody, nfkb-p50 antibody, NF-kappaB1 antibody, p50/p105 antibody, BICDR-1 antibody, bicdr1 antibody, ccdc64 antibody, SCY1 like pseudokinase 1 antibody, nuclear factor kappa B subunit 1 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog antibody, nuclear factor NF-kappa-B p105 subunit antibody, nucleoporin 107 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody, SCYL1 antibody, NFKB1 antibody, Nfkb1 antibody, nfkb1.L antibody, CpipJ_CPIJ012236 antibody, Nup107 antibody, nfkb1 antibody
Background
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
Molecular Weight
Calculated MW: 105 kDa
Pathways
p53 Signaling , NF-kappaB Signaling , RTK Signaling , TCR Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Myometrial Relaxation and Contraction , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , S100 Proteins
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