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TNFRSF13C antibody (Alexa Fluor 647)
TNFRSF13C
Reactivity: Human
FACS, IHC, IF, CyTOF
Host: Mouse
Monoclonal
11C1
Alexa Fluor 647
Product Details anti-TNFRSF13C Antibody (Alexa Fluor 647)
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Target
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TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Reactivity
All reactivities for TNFRSF13C antibodies
Human
Host
All hosts for TNFRSF13C antibodies
Mouse
Clonality
All clonalities for TNFRSF13C antibodies
Monoclonal
Conjugate
All conjugates for TNFRSF13C antibodies
This TNFRSF13C antibody is conjugated to Alexa Fluor 647
Application
All applications for TNFRSF13C antibodies
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Cytometry by Time of Flight (CyTOF)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
11C1
Isotype
IgG1 kappa
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Discover our top product TNFRSF13C Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for TNFRSF13C
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Target
TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Alternative Name
CD268 (TNFRSF13C Products )
Synonyms
RGD1560810 antibody, TNFRSF13C antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, TNF receptor superfamily member 13C antibody, uncharacterized LOC746611 antibody, tumor necrosis factor receptor superfamily, member 13c antibody, TNFRSF13C antibody, Tnfrsf13c antibody, LOC746611 antibody
Background
B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-κB activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-κB activation.
Pathways
NF-kappaB Signaling
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