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TNFRSF13C antibody (Alexa Fluor 647)
TNFRSF13C
Reactivity: Mouse
FACS, ICFC
Host: Rat
Monoclonal
7H22-E16
Alexa Fluor 647
Product Details anti-TNFRSF13C Antibody (Alexa Fluor 647)
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Target
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TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Reactivity
All reactivities for TNFRSF13C antibodies
Mouse
Host
All hosts for TNFRSF13C antibodies
Rat
Clonality
All clonalities for TNFRSF13C antibodies
Monoclonal
Conjugate
All conjugates for TNFRSF13C antibodies
This TNFRSF13C antibody is conjugated to Alexa Fluor 647
Application
All applications for TNFRSF13C antibodies
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
7H22-E16
Isotype
IgG1 kappa
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Discover our top product TNFRSF13C Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for TNFRSF13C
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Target
TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Alternative Name
CD268 (TNFRSF13C Products )
Synonyms
RGD1560810 antibody, TNFRSF13C antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, TNF receptor superfamily member 13C antibody, uncharacterized LOC746611 antibody, tumor necrosis factor receptor superfamily, member 13c antibody, TNFRSF13C antibody, Tnfrsf13c antibody, LOC746611 antibody
Background
BAFF (B cell-activating factor belonging to the TNF family) receptor (BAFF-R) is one of the three receptors that bind to BAFF. It is a type III transmembrane TNF receptor family member. BAFF-R is expressed at high levels in resting B cells and at lower levels in activated B cells, a small subset of activated/memory CD4+ T cells. It is a major mediator of BAFF dependent co-stimulatory response in peripheral B and T cells. It was reported that the mice expressing defective BAFF-R have disrupted B cell maturation. BAFF receptor appears to be particularly important for the regulation of normal B cell survival and maturation, as well as in the pathophysiology of aggressive B-cell malignancies and autoimmune diseases.
Pathways
NF-kappaB Signaling
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