×
For best experience we recommend to activate Javascript in your browser.
IL12 antibody
IL12
Reactivity: Mouse
WB, FACS, IHC, Func
Host: Rat
Monoclonal
C18-2
unconjugated
Product Details anti-IL12 Antibody
(hide)
Target
See all IL12 Antibodies
IL12
(Interleukin 12 (IL12))
Reactivity
All reactivities for IL12 antibodies
Mouse
Host
All hosts for IL12 antibodies
Rat
Clonality
All clonalities for IL12 antibodies
Monoclonal
Conjugate
All conjugates for IL12 antibodies
This IL12 antibody is un-conjugated
Application
All applications for IL12 antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)
Purification
The antibody was purified by affinity chromatography.
Clone
C18-2
Isotype
IgG2a kappa
Top Product
Discover our top product IL12 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for IL12
(hide)
Target
IL12
(Interleukin 12 (IL12))
Alternative Name
IL-12 (IL12 Products )
Synonyms
CLMF antibody, CLMF2 antibody, IL-12B antibody, NKSF antibody, NKSF2 antibody, p40 antibody, Il-12b antibody, Il12p40 antibody, Il-12p40 antibody, Il12 antibody, IL-12p40 antibody, IL-12 antibody, LOC100217488 antibody, IL-12p35 antibody, Il-12a antibody, Ll12a antibody, p35 antibody, IL12p40 antibody, IL12B antibody, IL-12 p35 antibody, interleukin 12B antibody, interleukin 12A antibody, interleukin 12b antibody, interleukin 12a antibody, Interleukin 12 level antibody, IL12B antibody, IL12A antibody, Il12b antibody, Il12a antibody, IL12 antibody, il12a antibody
Background
Interleukin 12 (IL-12) is a heterodimeric pleiotropic 70 kD (p70) cytokine consisting of a 40 kD (p40) subunit and a 35 kD (p35) subunit. IL-12 is a potent regulator of cell-mediated immune responses and key mediator of Th1 cell development. Bioactive IL-12 is secreted by activated B lymphocytes, dendritic cells, and macrophages in response to pathogens or upon interaction with activated T cells.IL-12 p70 stimulates cytotoxic T, NK and LAK cell proliferation, andinduces IFN-γ and TNF production in resting and activated T and NK cells.It has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular-immunity and as an anti-tumor and anti-viral agent.
Pathways
JAK-STAT Signaling , TLR Signaling , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation , Cancer Immune Checkpoints , Inflammasome
Recently viewed
(hide)