H2AFX antibody (pSer139)
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- Target See all H2AFX Antibodies
- H2AFX (H2A Histone Family, Member X (H2AFX))
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Binding Specificity
- pSer139
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This H2AFX antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Purification
- Protein A Chromatography
- Immunogen
- This Histone H2AX pSer139 antibody was raised against a peptide including pserine 139 of histone H2AX.
- Isotype
- IgG
- Top Product
- Discover our top product H2AFX Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Buffer
- 10 mM sodium phosphate pH 7.5, 150 mM NaCl, 30 % glycerol, 0.035 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Storage
- -20 °C
- Storage Comment
- Antibodies in solution can be stored at -20 °C for 2 years.
- Expiry Date
- 6 months
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Dual effect of heat shock on DNA replication and genome integrity." in: Molecular biology of the cell, Vol. 23, Issue 17, pp. 3450-60, (2012) (PubMed).
: "Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links." in: Molecular and cellular biology, Vol. 30, Issue 5, pp. 1217-30, (2010) (PubMed).
: "MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1." in: Molecular and cellular biology, Vol. 30, Issue 22, pp. 5335-47, (2010) (PubMed).
: "
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Dual effect of heat shock on DNA replication and genome integrity." in: Molecular biology of the cell, Vol. 23, Issue 17, pp. 3450-60, (2012) (PubMed).
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- Target
- H2AFX (H2A Histone Family, Member X (H2AFX))
- Alternative Name
- Histone H2A.X (H2AFX Products)
- Synonyms
- H2A.X antibody, H2A/X antibody, H2AX antibody, AW228881 antibody, H2ax antibody, Hist5-2ax antibody, gammaH2ax antibody, zgc:56329 antibody, h2a.x antibody, h2a/x antibody, h2ax antibody, RGD1566119 antibody, h2a antibody, h2afx antibody, H2A histone family member X antibody, H2A histone family, member X antibody, H2A histone family member X L homeolog antibody, histone cluster 1, H2ah antibody, histone cluster 2, H2ab S homeolog antibody, histone H2AX antibody, H2AFX antibody, H2afx antibody, h2afx antibody, h2afx.L antibody, HIST1H2AH antibody, hist2h2ab.S antibody, LOC100522201 antibody, LOC100720536 antibody
- Molecular Weight
- 15 kDa
- Gene ID
- 92815
- Pathways
- Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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