CBFA2T2 antibody (Middle Region)
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- Target See all CBFA2T2 Antibodies
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CBFA2T2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GQGRPLLPVG RGSSARSADC SVPSPALDKT SATTSRSSTP ASVTAIDTNG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against CBFA2T2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CBFA2T2
- Top Product
- Discover our top product CBFA2T2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 604 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- Alternative Name
- CBFA2T2 (CBFA2T2 Products)
- Synonyms
- MTGR1 antibody, A430091M07 antibody, C330013D05Rik antibody, Cbfa2t2h antibody, EHT antibody, ZMYND3 antibody, p85 antibody, XETOR antibody, cbfa2t2-a antibody, CBFA2/RUNX1 translocation partner 2 antibody, core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) antibody, CBFA2/RUNX1 translocation partner 2 L homeolog antibody, Cbfa2t2 antibody, CBFA2T2 antibody, cbfa2t2.L antibody
- Background
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In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-
Alias Symbols: DKFZp313F2116, EHT, MTGR1, ZMYND3, p85
Protein Interaction Partner: PRDM14, PDP1, CBFA2T2, TCP1, MDFI, RUNX1T1, LBP, APP, ATXN1L, ATN1, RERE, RUNX1, SIN3A, NCOR1, HDAC3, FBXL19, TAL2, NEUROG1, ID3, GTF2E1, WDYHV1, CBFA2T3, NCOR2, CBFB, TAL1,
Protein Size: 604 - Molecular Weight
- 67 kDa
- Gene ID
- 9139
- NCBI Accession
- NM_013277, NP_005084
- UniProt
- O43439
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