ERP44 antibody (Middle Region)
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- Target See all ERP44 Antibodies
- ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ERP44 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LHREFHHGPD PTDTAPGEQA QDVASSPPES SFQKLAPSEY RYTLLRDRDE
- Predicted Reactivity
- Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against TXNDC4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TXNDC4
- Top Product
- Discover our top product ERP44 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 406 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))
- Alternative Name
- TXNDC4 (ERP44 Products)
- Synonyms
- PDIA10 antibody, TXNDC4 antibody, 1110001E24Rik antibody, AI849526 antibody, AL033348 antibody, Txndc4 antibody, BWK4 antibody, txndc4 antibody, zgc:77883 antibody, endoplasmic reticulum protein 44 antibody, ERP44 antibody, Erp44 antibody, erp44 antibody
- Background
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TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Alias Symbols: ERP44, KIAA0573, PDIA10, TXNDC4
Protein Interaction Partner: FUS, UBC, SUMO1, NEDD8, NUDCD1, UBFD1, OSGEP, LARS, ISOC1, PLD3, PDCD10, FERMT2, YWHAZ, VCL, PFAS, PAK2, G6PD, FHL2, CNN2, TBCB, CKB, env, ELAVL1, SUMO4, RASSF5, USP32, USP46, UIMC1, ERO1LB, ERO1L, ITPR1, CD40,
Protein Size: 406 - Molecular Weight
- 45 kDa
- Gene ID
- 23071
- NCBI Accession
- NM_015051, NP_055866
- UniProt
- Q9BS26
- Pathways
- Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome
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