GADD34 antibody (N-Term)
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- Target See all GADD34 (PPP1R15A) Antibodies
- GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GADD34 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- GMYGEREATS VPRGQGSQFA DGQRAPLSPS LLIRTLQGSD KNPGEEKAEE
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PPP1R15A. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PPP1R15A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 674 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
- Alternative Name
- PPP1R15A (PPP1R15A Products)
- Synonyms
- 9630030H21 antibody, Gadd34 antibody, Myd116 antibody, GADD34 antibody, Peg-3 antibody, RGD1624209 antibody, protein phosphatase 1 regulatory subunit 15A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 15A antibody, protein phosphatase 1, regulatory subunit 15A antibody, PPP1R15A antibody, Ppp1r15a antibody
- Background
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This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
Alias Symbols: GADD34
Protein Interaction Partner: Dlg4, ZNF512B, PPP1CA, CTBP2, SMAD7, CAND1, COPS5, CUL3, RAD21, CUEDC2, IKBKB, HABP4, PPP1CC, PPP1R1A, TSN, KIF3A, EIF2S1, BCAR1, POU3F3, SMARCB1, BAG1, LYN, KMT2A, HSPA1A, GLC7, PPP1CB, HSPA8,
Protein Size: 674 - Molecular Weight
- 74 kDa
- Gene ID
- 23645
- NCBI Accession
- NM_014330, NP_055145
- UniProt
- O75807
- Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
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