TNFRSF10B antibody (Extracellular Domain)
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- Target See all TNFRSF10B Antibodies
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNFRSF10B antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- Recognizes an extracellular domain of TRAIL-R2 (DR5). TRAIL-R2 is one of two TNF superfamily member intracellular death domain containing receptors for TRAIL (APO2L)
- Purification
- Protein A purified
- Immunogen
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Recombinant fusion protein of human IgG heavy chain and extracellular domain of DR5.
Type of Immunogen: Fusion protein - Clone
- DR5-01-1
- Isotype
- IgG1
- Top Product
- Discover our top product TNFRSF10B Primary Antibody
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- Application Notes
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Approved: Flo (1 - 10 μg/mL)
Usage: Flow Cytometry: Recommended dilution - 1-10 μg/mL. Positive control - JURKAT human peripheral blood leukemia T cell line. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 15 mM sodium azide, approx, pH 7.4.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- avoid freeze thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- Target
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- Alternative Name
- TNFRSF10B / Killer / DR5 (TNFRSF10B Products)
- Synonyms
- TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
- Background
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Name/Gene ID: TNFRSF10B
Family: TNF Receptor
Synonyms: TNFRSF10B, Cytotoxic TRAIL receptor-2, CD262 antigen, DR5, Death receptor 5, KILLER, TRAIL-R2, TRICK2B, TRAILR2, TRICK2A, TRICKB, TRICK2, CD262, Fas-like protein, TRAIL receptor 2, ZTNFR9 - Gene ID
- 8795
- UniProt
- O14763
- Pathways
- p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
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