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Details for Product No. ABIN390770

HLA Class II DR alpha (HLA-DRA) (N-Term), (AA 48-75) antibody

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Synonyms HLA-DRA1, MLRW, DR-alpha, HLA-DRA, Mamu-DRA1
»Alternatives N-Term, AA 48-75
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN390770
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This HLA-DRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-75 AA from the N-terminal region of human HLA-DRA.
Clone RB19526
Isotype Ig
Specificity This HLA-DRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54~84 amino acids from the N-terminal region of human HLA-DRA .
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name HLA-DRA
Background HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages).
Synonyms: HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA, HLA-DRA1, HLA-DRA
Molecular Weight 28607 DA
Gene ID 3122
UniProt P01903
Research Area Cell Structure, Metabolism
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications De Jager, Jia, Wang et al.: "Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci." in: Nature genetics, Vol. 41, Issue 7, pp. 776-82, 2009 (PubMed).

Alternatives for antigen "HLA Class II DR alpha (HLA-DRA)", type "Antibodies"
Hosts (25), (14), (1)
Reactivities (36), (4), (3), (3)
Applications (35), (13), (12), (10), (8), (5), (5), (4), (4), (2), (1), (1)
Conjugates (4)
Epitopes (5), (5), (4), (3), (2), (1), (1)