Did you know that you can buy products from over 140 different suppliers from us?

Absent in Melanoma 2 (AIM2) (N-Term) antibody

Details for Product No. ABIN406126
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms AIM2, PYHIN4, Gm1313, Ifi210
Epitope
N-Term
(9), (9), (8), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Human
(67), (13), (12)
Host
Rabbit
(51), (10), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(57), (34), (10), (10), (8), (7), (6), (4), (3), (2)
Pubmed 1 reference available
Quantity 50 µg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN406126
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the N terminal of human AIM2
Sequence ESKYKEILLLTGLDNITDEELDRFKFFLSDEFNIATGKLH TANRIQVATL
Predicted Reactivity Horse : 100 %, Human : 100 %, Mouse : 70 %
Characteristics This is a rabbit polyclonal antibody against AIM2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name AIM2
Background AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
Molecular Weight 39 kDa
Gene ID 9447
NCBI Accession NM_004833, NP_004824
UniProt O14862
Research Area Cancer, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 343 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Absent in Melanoma 2 (AIM2) (N-Term) antibody WB Suggested Anti-AIM2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Lung
Background publications Woerner, Kloor, Schwitalle et al.: "The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers." in: Genes, chromosomes & cancer, Vol. 46, Issue 12, pp. 1080-9, 2007 (PubMed).

Validation Images
back to top