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Details for Product No. ABIN406126

Absent in Melanoma 2 (AIM2) (N-Term) antibody

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Antigen
Synonyms PYHIN4, Gm1313, Ifi210, AIM2
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN406126
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-AIM2 antibody: synthetic peptide directed towards the N terminal of human AIM2
Sequence ESKYKEILLLTGLDNITDEELDRFKFFLSDEFNIATGKLH TANRIQVATL
Predicted Reactivity Horse : 100%, Human : 100%, Mouse : 78%
Characteristics This is a rabbit polyclonal antibody against AIM2. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name AIM2
Background AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
Molecular Weight 39kDa
Gene ID 9447
NCBI Accession NP_004824, NM_004833
UniProt O14862
Research Area Cancer, Transcription Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-AIM2 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Woerner, Kloor, Schwitalle et al.: "The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers." in: Genes, chromosomes & cancer, Vol. 46, Issue 12, pp. 1080-9, 2007 (PubMed).

Alternatives for antigen "Absent in Melanoma 2 (AIM2)", type "Antibodies"
Hosts (38), (8), (6)
Reactivities (51), (14), (13)
Applications (41), (26), (10), (7), (6), (4), (4), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (6), (4), (2), (2), (1), (1), (1), (1), (1), (1)
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