EDNRB antibody (C-Term)

Catalog No. ABIN452934

Product Details anti-EDNRB Antibody

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDNRB antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Endothelin B receptor at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human EDNRB

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.29 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for EDNRB

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Alternative Name: Endothelin B Receptor (EDNRB Products)

Synonyms: ABCDS antibody, ET-B antibody, ET-BR antibody, ETB antibody, ETBR antibody, ETRB antibody, HSCR antibody, HSCR2 antibody, WS4A antibody, Ednra antibody, Etb antibody, ETR-b antibody, ETb antibody, Sox10m1 antibody, EDNRB antibody, abcds antibody, etb antibody, etrb antibody, hscr antibody, hscr2 antibody, endothelin receptor type B antibody, EDNRB antibody, Ednrb antibody, ednrb antibody

Background: EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.Synonyms: ABCDS, EDNRB, ET-B, ET-BR, ETB, ETBR, ETRB, Endothelin receptor non-selective type, HSCR, HSCR2, WS4A, endothelin receptor type B

Molecular Weight: 49644 Da

Gene ID: 1910

NCBI Accession: NP_000106

UniProt: P24530

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process