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FAK antibody (PTK2 Protein tyrosine Kinase 2) (C-Term)

Details for Product anti-PTK2 Antibody No. ABIN453801, Supplier: Login to see New
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Antigen
Synonyms FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, Fadk, mKIAA4203
Epitope
C-Term
(69), (60), (58), (50), (47), (33), (22), (22), (20), (15), (14), (14), (13), (13), (13), (13), (12), (11), (9), (9), (8), (7), (7), (7), (7), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(649), (364), (334), (21), (6), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(590), (92), (2), (2), (1)
Clonality
Polyclonal
Conjugate
This FAK antibody is un-conjugated
(18), (17), (16), (13), (12), (12), (11), (11), (11), (11), (11), (11), (3), (2), (2), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(475), (182), (157), (124), (108), (87), (54), (24), (15), (6), (6), (5), (4), (3), (2), (1)
Pubmed 3 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human PTK2
Specificity This antibody reacts to PTK2.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name FAK1 / PTK2 (PTK2 Antibody Abstract)
Background PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.Synonyms: FADK1, FAK, Focal adhesion kinase 1, Protein-tyrosine kinase 2, pp125FAK
Gene ID 5747
NCBI Accession NP_005598
UniProt Q05397
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-FAK antibody (PTK2 Protein tyrosine Kinase 2) (C-Term) (ABIN453801) Western blot analysis of PTK2 (arrow) using rabbit polyclonal PTK2 Antibody (C-term) ...
Background publications Gervais, Thornberry, Ruffolo et al.: "Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide." in: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 17102-8, 1998 (PubMed).

Calalb, Polte, Hanks: "Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases." in: Molecular and cellular biology, Vol. 15, Issue 2, pp. 954-63, 1995 (PubMed).

Polte, Hanks: "Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 23, pp. 10678-82, 1995 (PubMed).

Catalog No. ABIN453801
$401.50
Plus shipping costs $45.00

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