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HLA-E antibody (Biotin)

HLA-E Reactivity: Human FACS, IF Host: Mouse Monoclonal MEM-E-07 Biotin
Catalog No. ABIN490333
  • Target See all HLA-E Antibodies
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Reactivity
    • 66
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 43
    • 23
    Mouse
    Clonality
    • 45
    • 21
    Monoclonal
    Conjugate
    • 30
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-E antibody is conjugated to Biotin
    Application
    • 42
    • 26
    • 18
    • 13
    • 13
    • 12
    • 9
    • 7
    • 3
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Specificity
    The antibody MEM-E/07 recognized native surface-expressed HLA-E, but not denatured heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells. The published results revealed that the antibody cross-reacts with some classical MHC Class I molecules (MHC Class Ia): HLA-B7 (strongly), HLA-B8 (moderately), HLA-B27, -B44 (weakly).
    Purification
    Protein A purified
    Immunogen
    Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide.

    Type of Immunogen: Synthetic peptide
    Clone
    MEM-E-07
    Isotype
    IgG1
    Top Product
    Discover our top product HLA-E Primary Antibody
  • Application Notes
    Approved: Flo, IF

    Usage: Biotinylated antibody is designed for indirect immunofluorescence analysis by Flow Cytometry. Suggested working dilution is 2 microgram/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determin The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, 15 mM sodium azide,  pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    avoid freeze thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
  • Target
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Alternative Name
    HLA-E (HLA-E Products)
    Synonyms
    EA1.2 antibody, EA2.1 antibody, HLA-6.2 antibody, MHC antibody, QA1 antibody, major histocompatibility complex, class I, E antibody, HLA-E antibody, PATR-E antibody
    UniProt
    P13747
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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