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PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (AA 187-276)

Details for Product anti-PDK2 Antibody No. ABIN562160, Supplier: Log in to see
Antigen
  • 3j828
  • MGC52849
  • MGC132353
  • PDHK2
  • Pdk
  • PDK2
  • PDKII
  • zgc:56209
Alternatives
anti-Human PDK2 antibody for Enzyme Immunoassay
Epitope
AA 187-276, partial
21
17
16
15
7
5
5
3
2
2
2
2
2
1
1
1
1
Reactivity
Human
120
60
33
5
3
1
Host
Mouse
103
37
Clonality (Clone)
Monoclonal ()
Conjugate
This PDK2 antibody is un-conjugated
9
9
8
7
7
7
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi), ELISA, Western Blotting (WB)
119
83
60
25
17
11
4
3
1
1
Supplier
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Available images

Immunogen PDK2 (AAH05811, 187 a.a. ~ 276 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: HIGSIDPNCN VSEVVKDAYD MAKLLCDKYY MASPDLEIQE INAANSKQPI HMVYVPSHLY HMLFELFKNA MRATVESHES SLILPPIKVM
Clone 2G1
Isotype IgG2a kappa
Cross-Reactivity Human
Alternative Name PDK2 (PDK2 Antibody Abstract)
Background Full Gene Name: pyruvate dehydrogenase kinase, isozyme 2
Synonyms: PDHK2
Gene ID 5164
Research Area Cancer, Metabolism
Pathways PI3K-Akt Signaling, RTK Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (AA 187-276) (ABIN562160) PDK2 monoclonal antibody (M01), clone 2G1 Western Blot analysis of PDK2 expression in...
Western Blotting (WB) image for anti-PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (AA 187-276) (ABIN562160) Western blot analysis of PDK2 over-expressed 293 cell line, cotransfected with PDK2 V...
Immunostaining (ISt) image for anti-PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (AA 187-276) (ABIN562160) Immunoperoxidase of monoclonal antibody to PDK2 on formalin-fixed paraffin-embedded h...
ELISA image for anti-PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (AA 187-276) (ABIN562160) Detection limit for recombinant GST tagged PDK2 is approximately 0.3ng/ml as a captur...
Western Blotting (WB) image for anti-PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (AA 187-276) (ABIN562160) Western Blot analysis of PDK2 expression in transfected 293T cell line by PDK2 monocl...
 image for anti-PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (AA 187-276) (ABIN562160) Western Blot detection against Immunogen (35.31 KDa) .
Product cited in: Gannon, Ables, Crawford, Lowe, Offield, Magnuson, Wright: "pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis." in: Developmental biology, Vol. 314, Issue 2, pp. 406-17, 2008

Babu, Deering, Mirmira: "A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis." in: Molecular genetics and metabolism, Vol. 92, Issue 1-2, pp. 43-55, 2007

Gu, Dubauskaite, Melton: "Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors." in: Development (Cambridge, England), Vol. 129, Issue 10, pp. 2447-57, 2002

Ohlsson, Karlsson, Edlund: "IPF1, a homeodomain-containing transactivator of the insulin gene." in: The EMBO journal, Vol. 12, Issue 11, pp. 4251-9, 1993