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CYP1A1 antibody (AA 1-512)
CYP1A1
Reactivity: Human
WB
Host: Mouse
Polyclonal
unconjugated
Product Details anti-CYP1A1 Antibody
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Target
See all CYP1A1 Antibodies
CYP1A1
(Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
Binding Specificity
All epitopes for CYP1A1 antibodies
AA 1-512
Reactivity
All reactivities for CYP1A1 antibodies
Human
Host
All hosts for CYP1A1 antibodies
Mouse
Clonality
All clonalities for CYP1A1 antibodies
Polyclonal
Conjugate
All conjugates for CYP1A1 antibodies
This CYP1A1 antibody is un-conjugated
Application
All applications for CYP1A1 antibodies
Western Blotting (WB)
Purpose
Mouse polyclonal antibody raised against a full-length human CYP1A1 protein.
Sequence
MLFPISMSAT EFLLASVIFC LVFWVIRASR PQVPKGLKNP PGPWGWPLIG HMLTLGKNPH LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG DDFKGRPDLY TFTLISNGQS MSFSPDSGPV WAARRRLAQN GLKSFSIASD PASSTSCYLE EHVSKEAEVL ISTLQELMAG PGHFNPYRYV VVSVTNVICA ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL RYLPNPSLNA FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV IGRSRRPRLS DRSHLPYMEA FILETFRHSS FVPFTIPHST TRDTSLKGFY IPKGRCVFVN QWQINHDQKL WVNPSEFLPE RFLTPDGAID KVLSEKVIIF GMGKRKCIGE TIARWEVFLF LAILLQRVEF SVPLGVKVDM TPIYGLTMKH ACCEHFQMQL RS
Cross-Reactivity
Human
Characteristics
Antibody reactive against mammalian transfected lysate.
Immunogen
CYP1A1 (NP_000490.1, 1 a.a. ~ 512 a.a) full-length human protein.
Top Product
Discover our top product CYP1A1 Primary Antibody
Alternatives
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anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) (Middle Region) antibody
CYP1A1
Reactivity: Human, Mouse, Rat, Horse, Cow, Guinea Pig, Rabbit, Sheep, Dog, Zebrafish (Danio rerio)
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
References for anti-CYP1A1 antibody (ABIN947763)
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Zapletal, Tylichová, Neča, Kohoutek, Machala, Milcová, Pokorná, Topinka, Moyer, Hofmanová, Kozubík, Vondráček : "Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models. " in: Archives of toxicology , Vol. 91 , Issue 5 , pp. 2135-2150 , (2016 ) (PubMed ).
Kabátková, Zapletal, Tylichová, Ne?a, Machala, Milcová, Topinka, Kozubík, Vondrá?ek : "Inhibition of ?-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation. " in: Mutagenesis , Vol. 30 , Issue 4 , pp. 565-76 , (2015 ) (PubMed ).
Target Details for CYP1A1
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Target
CYP1A1
(Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
Alternative Name
CYP1A1 (CYP1A1 Products )
Synonyms
AHH antibody, AHRR antibody, CP11 antibody, CYP1 antibody, P1-450 antibody, P450-C antibody, P450DX antibody, Cyp1a2 antibody, P450-1 antibody, cyp1a1 antibody, CYP1A1 antibody, CYPIA1 antibody, Cyp45c antibody, Cypc45c antibody, P-450MC antibody, wu:fb63b04 antibody, zfCYP1A antibody, zgc:109747 antibody, ahh antibody, ahrr antibody, cp11 antibody, cyp1 antibody, cyp1a antibody, p1-450 antibody, p450-c antibody, p450dx antibody, cytochrome P450 family 1 subfamily A member 1 antibody, cytochrome P450 1A1 antibody, cytochrome P450, family 1, subfamily a, polypeptide 1 antibody, cytochrome P450, family 1, subfamily A, polypeptide 1 antibody, cytochrome P450 family 1 subfamily D polypeptide 1 antibody, cytochrome P4501A1 antibody, polycyclic hydrocarbon-inducible cytochrome P450c antibody, cytochrome P450, family 1, subfamily A antibody, cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 antibody, cytochrome P450 family 1 subfamily A member 1 L homeolog antibody, CYP1A1 antibody, CpipJ_CPIJ010542 antibody, Cyp1a1 antibody, cyp1d1 antibody, LOC100328613 antibody, cyp1a antibody, LOC102129994 antibody, cyp1a1.L antibody
Background
Full Gene Name: cytochrome P450, family 1, subfamily A, polypeptide 1 Synonyms: AHH,AHRR,CP11,CYP1,P1-450,P450-C,P450DX
Gene ID
1543
NCBI Accession
NM_000499
Pathways
Steroid Hormone Biosynthesis , Regulation of Lipid Metabolism by PPARalpha
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