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MGMT antibody (N-Term)
MGMT
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MGMT Antibody
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Target
See all MGMT Antibodies
MGMT
(O6-Methylguanine-DNA-Methyltransferase (MGMT))
Binding Specificity
All epitopes for MGMT antibodies
AA 1-30, N-Term
Reactivity
All reactivities for MGMT antibodies
Human
Host
All hosts for MGMT antibodies
Rabbit
Clonality
All clonalities for MGMT antibodies
Polyclonal
Conjugate
All conjugates for MGMT antibodies
This MGMT antibody is un-conjugated
Application
All applications for MGMT antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
Synthetic peptide (between 1-30 aa) - KLH conjugated - corresponding to the N-terminal region of human MGMT.
Isotype
Ig Fraction
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Discover our top product MGMT Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for MGMT
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Target
MGMT
(O6-Methylguanine-DNA-Methyltransferase (MGMT))
Alternative Name
MGMT (MGMT Products )
Synonyms
AGT antibody, AI267024 antibody, Agat antibody, O-6-methylguanine-DNA methyltransferase antibody, MGMT antibody, Mgmt antibody
Background
MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. It repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.Synonyms: 6-O-methylguanine-DNA methyltransferase, Methylated-DNA-protein-cysteine methyltransferase, O-6-methylguanine-DNA-alkyltransferase
Gene ID
9606
Pathways
DNA Damage Repair , Positive Regulation of Response to DNA Damage Stimulus
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