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JAK2 antibody (Janus Kinase 2)

Details for Product anti-JAK2 Antibody No. ABIN966432, Supplier: Log in to see
Antigen
  • JAK2bCA
  • jak2
  • JTK10
  • THCYT3
  • AI504024
  • C81284
  • Fd17
  • JAK-2
  • Janus kinase 2b
  • Janus kinase 2
  • tyrosine-protein kinase JAK2-like
  • jak2b
  • JAK2
  • Jak2
  • LOC100051487
Alternatives
anti-Human JAK2 antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus)
240
153
141
8
6
6
6
2
1
1
Host
Rabbit
232
20
4
Clonality
Polyclonal
Conjugate
This JAK2 antibody is un-conjugated
9
6
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC)
170
112
96
27
25
24
16
10
9
9
3
3
Options
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 221 (Q-D-YP-H-I).
Specificity JAK2 (Ab-221) antibody detects endogenous levels of total JAK2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name JAK2 (JAK2 Antibody Abstract)
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Feener, Rosario, Dunn, Stancheva, Myers: "Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4968-78, 2004 (PubMed).

Argetsinger, Kouadio, Steen, Stensballe, Jensen, Carter-Su: "Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4955-67, 2004 (PubMed).