NFB-p105/p50 (Ab-932) antibody detects endogenous levels of total NFB-p105/p50 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human NFB-p105/p50 around the phosphorylation site of serine 932 (E-T-SP-F-R).
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Chen, Bhatia, Chang, Castranova: "Finding NEMO by K63-linked polyubiquitin chain." in: Cell death and differentiation, Vol. 13, Issue 11, pp. 1835-8, (2006) (PubMed).
Steinbrecher, Wilson, Cogswell, Baldwin: "Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription." in: Molecular and cellular biology, Vol. 25, Issue 19, pp. 8444-55, (2005) (PubMed).
Beinke, Ley: "Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology." in: The Biochemical journal, Vol. 382, Issue Pt 2, pp. 393-409, (2004) (PubMed).
Target
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))