anti-Human CD11b antibody for Immunocytochemistry

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha M
  • integrin, alpha M
  • ITGAM
  • Itgam
Epitope
AA 623-728
48
39
24
19
16
15
15
13
8
6
6
5
5
5
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
732
515
192
79
31
19
17
15
13
11
10
9
8
7
5
4
4
4
4
2
Host
Mouse
532
410
168
17
6
2
Clonality
Monoclonal
Conjugate
This CD11b antibody is un-conjugated
150
128
94
56
24
24
20
17
15
14
14
13
13
13
11
11
11
10
9
7
7
6
6
6
6
6
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
931
238
235
173
171
138
99
98
96
68
25
21
21
18
14
8
5
5
4
3
3
1
1
1
1
1
1
1
1
1
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Catalog No. ABIN1724905
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
26.453575 ABIN4900696 CyTOF FACS ICC IHC Mouse IgG1 Log in to see ICRF44 3
26.453575 ABIN4899288 CyTOF FACS ICC IHC Mouse IgG2b AA 17-1105 Log in to see 238446
1 ABIN258322 ICC FACS IF IHC (p) IHC WB Rabbit Internal Region, AA 500-600 Log in to see Polyclonal 16
1 ABIN409930 FACS ICC IF IHC IHC (fro) IHC (p) SimWes WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal 24
1 ABIN4289459 FACS ICC IF IHC (fro) IHC (p) Alexa Fluor 488 Rat IgG2b Log in to see M1-70-15
1 ABIN4289448 FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Rabbit AA 250-350, Internal Region Log in to see Polyclonal 1
1 ABIN1732807 ICC FACS IF IHC (p) WB Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289435 CyTOF FACS ICC IF IHC IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70-15
1 ABIN1732800 FACS ICC IF IHC (p) WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal
1 ABIN1981858 Func IHC (f) ICC FACS IP Biotin Mouse IgG1 Log in to see ICRF44 4
1 ABIN4289434 CyTOF FACS ICC IF IHC IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70-15
1 ABIN1027692 FACS Func ICC IHC (f) IP Mouse IgG1 Log in to see ICRF44 3
1 ABIN4880796 ELISA ICC WB Mouse IgG1 AA 623-728 Log in to see 3A10H5
1 ABIN2749012 Func IHC (f) ICC FACS IP Mouse IgG1 Log in to see ICRF44 3
1 ABIN409442 FACS ICC IF IHC IHC (p) WB DyLight 488 Rabbit Internal Region, AA 500-600 Log in to see Polyclonal
1 ABIN314167 ICC IF IHC IHC (p) WB Biotin Rabbit Internal Region, AA 500-600 Log in to see Polyclonal
1 ABIN4289478 FACS ICC IF IHC IHC (p) FITC Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289477 FACS ICC IF IHC IHC (p) WB DyLight 550 Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289476 FACS ICC IF IHC IHC (p) WB DyLight 650 Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289480 FACS ICC IF IHC IHC (p) WB DyLight 405 Rabbit AA 500-600, Internal Region Log in to see Polyclonal

General

Antigen Integrin alpha M (ITGAM) Antibodies
Epitope AA 623-728
(48), (39), (24), (19), (16), (15), (15), (13), (8), (6), (6), (5), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(732), (515), (192), (79), (31), (19), (17), (15), (13), (11), (10), (9), (8), (7), (5), (4), (4), (4), (4), (2)
Host Mouse
(532), (410), (168), (17), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD11b antibody is un-conjugated
(150), (128), (94), (56), (24), (24), (20), (17), (15), (14), (14), (13), (13), (13), (11), (11), (11), (10), (9), (7), (7), (6), (6), (6), (6), (6), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(931), (238), (235), (173), (171), (138), (99), (98), (96), (68), (25), (21), (21), (18), (14), (8), (5), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN1724905) Images
Purification Purified
Immunogen Purified recombinant fragment of human ITGAM (AA 623-728) expressed in E. Coli.
Clone 3A10H5
Isotype IgG1

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b antibody (ABIN1724905) Images back to top
Antigen
Alternative Name ITGAM (ITGAM Antibody Abstract)
Background This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. ,
Molecular Weight 127.1 kDa
Gene ID 3684
HGNC 3684
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b antibody (ABIN1724905) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b antibody (ABIN1724905) Images back to top
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-CD11b antibody (ABIN1724905)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Product cited in:

Rhodes, Fürnrohr, Roberts, Tzircotis, Schett, Spector, Vyse: "The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes." in: Annals of the rheumatic diseases, Vol. 71, Issue 12, pp. 2028-34, 2012

Grüger, Reiners, Schnitzler, Brandenburg, Zündorf: "Garenoxacin-induced increase of CD11b expression on human polymorphonuclear neutrophils does not affect phagocytosis and killing of Staphylococcus aureus." in: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, Vol. 17, Issue 2, pp. 291-6, 2011

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN1724905) back to top
Supplier Images
ELISA image for anti-Integrin alpha M (ITGAM) (AA 623-728) antibody (ABIN1724905) anti-Integrin alpha M (ITGAM) (AA 623-728) antibody
Immunocytochemistry (ICC) image for anti-Integrin alpha M (ITGAM) (AA 623-728) antibody (ABIN1724905) anti-Integrin alpha M (ITGAM) (AA 623-728) antibody (Image 2)
Western Blotting (WB) image for anti-Integrin alpha M (ITGAM) (AA 623-728) antibody (ABIN1724905) anti-Integrin alpha M (ITGAM) (AA 623-728) antibody (Image 3)
Western Blotting (WB) image for anti-Integrin alpha M (ITGAM) (AA 623-728) antibody (ABIN1724905) anti-Integrin alpha M (ITGAM) (AA 623-728) antibody (Image 4)