anti-Non-Human Primate CD11b antibody for Immunocytochemistry

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha M
  • integrin, alpha M
  • ITGAM
  • Itgam
Reactivity
Human, Non-Human Primate
732
515
192
79
31
19
17
15
13
11
9
9
8
7
5
4
4
4
4
2
Host
Mouse
532
410
168
17
6
2
Clonality
Monoclonal
Conjugate
This CD11b antibody is conjugated to Biotin
150
128
93
56
24
24
20
17
15
14
14
13
13
13
11
11
11
10
9
7
7
6
6
6
6
6
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)
930
237
235
173
172
138
99
98
97
67
25
21
21
18
13
8
5
5
4
3
3
1
1
1
1
1
1
1
1
1
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Catalog No. ABIN1981858
$ 288.75
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1027692 FACS Func ICC IHC (f) IP Mouse IgG1 Log in to see ICRF44 3
1 ABIN2749012 Func IHC (f) ICC FACS IP Mouse IgG1 Log in to see ICRF44 3
1 ABIN2749103 Func IHC (f) ICC FACS IP PE Mouse IgG1 Log in to see ICRF44 4
1 ABIN2749102 Func IHC (f) ICC FACS IP FITC Mouse IgG1 Log in to see ICRF44 4

General

Antigen Integrin alpha M (ITGAM) Antibodies
Reactivity Human, Non-Human Primate
(732), (515), (192), (79), (31), (19), (17), (15), (13), (11), (9), (9), (8), (7), (5), (4), (4), (4), (4), (2)
Host Mouse
(532), (410), (168), (17), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD11b antibody is conjugated to Biotin
(150), (128), (93), (56), (24), (24), (20), (17), (15), (14), (14), (13), (13), (13), (11), (11), (11), (10), (9), (7), (7), (6), (6), (6), (6), (6), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)
(930), (237), (235), (173), (172), (138), (99), (98), (97), (67), (25), (21), (21), (18), (13), (8), (5), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN1981858) Images
Specificity The mouse monoclonal antibody ICRF44 recognizes CD11b (Mac-1alpha), a 165-170 kDa type 1 transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells.
HLDA IV, WS Code M047
Characteristics The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Immunogen Rheumatoid synovial cells and human monocytes.
Clone ICRF44
Isotype IgG1

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b antibody (ABIN1981858) Images back to top
Antigen
Alternative Name CD11b (ITGAM Antibody Abstract)
Background CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18), expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.
Gene ID 3684
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Glia marker, CD Antigens, Surface Receptors of Immune Cells
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b antibody (ABIN1981858) Images back to top
Application Notes Biotinylated antibody is designed for indirect immunofluorescence analysis by Flow Cytometry.
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b antibody (ABIN1981858) Images back to top
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Handling Advice Do not freeze. Do not use after expiration date stamped on vial label.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-CD11b antibody (ABIN1981858)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Product cited in:

Tieu, Lee, Sun, Lejeune, Recinos, Ju, Spratt, Guo, Milewicz, Tilton, Brasier: "An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice." in: The Journal of clinical investigation, Vol. 119, Issue 12, pp. 3637-51, 2009

Masten, Olson, Tarleton, Rund, Schuyler, Mehran, Archibeque, Lipscomb: "Characterization of myeloid and plasmacytoid dendritic cells in human lung." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 11, pp. 7784-93, 2006

Hua, Sakamoto, Nagaoka: "Inhibitory actions of glucosamine, a therapeutic agent for osteoarthritis, on the functions of neutrophils." in: Journal of leukocyte biology, Vol. 71, Issue 4, pp. 632-40, 2002

Sánchez-Torres, García-Romo, Cornejo-Cortés, Rivas-Carvalho, Sánchez-Schmitz: "CD16+ and CD16- human blood monocyte subsets differentiate in vitro to dendritic cells with different abilities to stimulate CD4+ T cells." in: International immunology, Vol. 13, Issue 12, pp. 1571-81, 2001