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Browse our anti-SMAD3 (SMAD3) Antibodies

Full name:
anti-SMAD, Mothers Against DPP Homolog 3 Antibodies (SMAD3)
On are 460 SMAD, Mothers Against DPP Homolog 3 (SMAD3) Antibodies from 27 different suppliers available. Additionally we are shipping SMAD3 Kits (47) and SMAD3 Proteins (24) and many more products for this protein. A total of 574 SMAD3 products are currently listed.
AU022421, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, mad3, Madh3, madh3-A, madh3a, Smad 3, smad3, wu:fa99e03, XenMLP, Xmad3, XSmad3
list all antibodies Gene Name GeneID UniProt
SMAD3 4088 P84022
SMAD3 17127 Q8BUN5
SMAD3 25631 P84025

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Most Popular Reactivities for anti-SMAD3 (SMAD3) Antibodies

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anti-Human SMAD3 Antibodies:

anti-Mouse (Murine) SMAD3 Antibodies:

anti-Rat (Rattus) SMAD3 Antibodies:

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Top referenced anti-SMAD3 Antibodies

  1. Human Polyclonal SMAD3 Primary Antibody for EIA, IHC (p) - ABIN358226 : Venables, Bourgeois, Dalgliesh, Kister, Stevenin, Elliott: Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon. in Human molecular genetics 2005 (PubMed)
    Show all 5 references for ABIN358226

  2. Human Polyclonal SMAD3 Primary Antibody for EIA, IHC (p) - ABIN358225 : Imoto, Sugiyama, Sekine, Matsuda: Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-beta signaling. in FEBS letters 2005 (PubMed)
    Show all 5 references for ABIN358225

  3. Human Polyclonal SMAD3 Primary Antibody for FACS, IF - ABIN954841 : Zhang, Wang, Tan, Li, Zhang, Chen: Smad3 prevents beta-catenin degradation and facilitates beta-catenin nuclear translocation in chondrocytes. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 references for ABIN954841

  4. Chicken Polyclonal SMAD3 Primary Antibody for EIA, IHC (p) - ABIN401333 : Shi, Massagué: Mechanisms of TGF-beta signaling from cell membrane to the nucleus. in Cell 2003 (PubMed)
    Show all 3 references for ABIN401333

  5. Human Polyclonal SMAD3 Primary Antibody for EIA, WB - ABIN401376 : Derynck, Zhang: Smad-dependent and Smad-independent pathways in TGF-beta family signalling. in Nature 2003 (PubMed)
    Show all 3 references for ABIN401376

  6. Human Polyclonal SMAD3 Primary Antibody for ELISA, WB - ABIN1531634 : Zhang, Feng, We, Derynck: Receptor-associated Mad homologues synergize as effectors of the TGF-beta response. in Nature 1996 (PubMed)
    Show all 2 references for ABIN1531634

  7. Chicken Polyclonal SMAD3 Primary Antibody for EIA, IF - ABIN303328 : Carracedo, Lu, Popova, Jonsson, Eckes, Gullberg: The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 references for ABIN303328

  8. Human Polyclonal SMAD3 Primary Antibody for DB, IF - ABIN389656 : Cohen-Solal, Merrigan, Chan, Goydos, Chen, Foran, Liu, Lasfar, Reiss: Constitutive Smad linker phosphorylation in melanoma: a mechanism of resistance to transforming growth factor-?-mediated growth inhibition. in Pigment cell & melanoma research 2011 (PubMed)

  9. Chicken Polyclonal SMAD3 Primary Antibody for IHC, WB - ABIN2792537 : Cheng, Chang, Chao, Lee: Hepatitis C viral proteins interact with Smad3 and differentially regulate TGF-beta/Smad3-mediated transcriptional activation. in Oncogene 2004 (PubMed)

More Antibodies against SMAD3 Interaction Partners

Zebrafish SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. Smad3 is mainly active in post-mitotic, non-proliferating cells with a role in TGF-beta (show TGFB1 Antibodies) control of zebrafish spinal cord development

  2. Nodal signaling and mesendoderm induction depend on Smad2 (show SMAD2 Antibodies)/3 and suggest that transforming growth factor-beta signals other than Nodal also contribute to Smad2 (show SMAD2 Antibodies)/3 signaling and embryonic patterning.

  3. although the role of Smad (show SMAD1 Antibodies) proteins in mediating Nodal signaling is well-documented, the functional characterization of Ttrap (show TDP2 Antibodies) provides insight into a novel Smad (show SMAD1 Antibodies) partner that plays an essential role in the fine-tuning of this signal transduction cascade

  4. Smad2 (show SMAD2 Antibodies)/3 activities play important roles not only in mesendodermal development but also in neural development during early vertebrate embryogenesis

Human SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. results demonstrated that the novel pathway H19 (show NCKAP1 Antibodies)/miR (show MLXIP Antibodies)-675/TGF-beta1 (show TGFB1 Antibodies)/Smad3/HDAC (show HDAC3 Antibodies) regulates osteogenic differentiation of hMSCs and may serve as a potential target for enhancing bone formation in vivo.

  2. Induction of pSmad3L through BLT1-NOX-ROS (show ROS1 Antibodies)-EGFR (show EGFR Antibodies)-PI3K (show PIK3CA Antibodies)-ERK1/2 (show MAPK1/3 Antibodies) signaling pathway is a key mechanism by which LTB4 (show PTGR1 Antibodies) blocks the anti-proliferative responses of TGF-beta1 (show TGFB1 Antibodies) in breast tumors.

  3. results indicate that miR-16 (show GDE1 Antibodies)-5p is an important regulator of SMAD3 expression in human chondrocytes and may contribute to the development of osteoarthritis

  4. Up-regulation of smad3 is associated with endometrial cancer.

  5. SMAD3 is a necessary factor for TGFbeta (show TGFB1 Antibodies)-mediated stimulation of mRNA and protein expression of type IV collagen (show COL4 Antibodies) genes in human vascular smooth muscle cells; it regulates expression of COL4a1 (show COL4A1 Antibodies) and COL4a2 (show COL4a2 Antibodies)

  6. These results for the first time demonstrate a role of Cdk5 (show CDK5 Antibodies)/p35 (show ANXA1 Antibodies) in the regulation of cell cycle progression modulated by TGF-beta1 (show TGFB1 Antibodies).

  7. hCLP46 increases Smad3 protein stability via inhibiting its ubiquitin-proteasomal degradation

  8. Data show that the expression of transforming growth factor beta 1 (TGFB1 (show TGFB1 Antibodies)) was correlated with the expression of SMA- and MAD-related protein 3 (SMAD3) and matrix metalloproteinase-13 (MMP13 (show MMP13 Antibodies)) in osteoarthritis (OA)-affected cartilage.

  9. Different signaling pathways are involved in osteitis in CRS (show CARS Antibodies) and are activated by the TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling pathway in CRSwNP versus the TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies)-independent signaling pathway in CRSsNP.

  10. Astragaloside can delay the renal fibrosis process in diabetic mice by influencing the TGF-beta (show TGFB1 Antibodies)/SMADS signaling pathway and down-regulating TGF-beta1 (show TGFB1 Antibodies), SMAD2 (show SMAD2 Antibodies)/3, and alpha-SMA (show SMN1 Antibodies) expression.

Xenopus laevis SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. E2a (show TCF3 Antibodies) is necessary to drive transcription of Smad2 (show SMAD2 Antibodies)/3 target genes, including critical regulators of dorsal cell fate and morphogenesis

Pig (Porcine) SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. Smad3 regulate the activity and stability of myocardin (show MYOCD Antibodies)-related transcription factor during epithelial-myofibroblast transition

  2. SP1 (show SP1 Antibodies) and SMAD3 are required for high glucose-induced p21(WAF1 (show CDKN1A Antibodies)) gene transcription in LLC-PK1 (show PKLR Antibodies) cells.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. Arsenite disrupts zinc-dependent TGFbeta2-SMAD2 (show SMAD2 Antibodies)/3 activity during murine cardiac progenitor cell differentiation.

  2. This study showed that Smad3 deficiency inhibits LTP (show SCP2 Antibodies) induction by enhancing phasic and tonic GABAA (show GABRg1 Antibodies) receptor-mediated neurotransmission.

  3. Suggest that hyperoxia-increased high-tidal-volume ventilation-induced acute lung injury partially depends on the Src (show SRC Antibodies) and Smad3 pathways.

  4. Smad3 is a key transcriptional factor of TGF-beta (show TGFB1 Antibodies) signaling that differentially regulates T cell immune responses in a mouse model of cardiac allograft rejection

  5. Smad2 (show SMAD2 Antibodies) and Smad3 oppositely modify STAT3 (show STAT3 Antibodies)-induced transcription of IL-17A (show IL17A Antibodies) and retinoic acid receptor (show RARA Antibodies)-related orphan nuclear receptor (show NR1D1 Antibodies), RORgammat encoded by Rorc (show RORC Antibodies), by acting as a co-activator and co-repressor of STAT3 (show STAT3 Antibodies), respectively.

  6. Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P (show S1PR1 Antibodies))/S1P3 (show S1PR3 Antibodies) signaling axis

  7. pSmad3L-Ser (show SIGLEC1 Antibodies) signalling correlates with carcinogenesis of colon tumors and this work supports the hypothesis that pSmad2/3L-Thr (show TRH Antibodies) immunostaining-positive cells are cancer

  8. SMAD3 deficiency promotes vessel wall remodeling, collagen fiber reorganization and leukocyte infiltration in an inflammatory abdominal aortic aneurysm mouse model.

  9. These results suggest that TGF-beta regulates RANKL-induced osteoclastogenesis through reciprocal cooperation between Smad2/3 and c-Fos.

  10. Treatment with geniposide almost completely blocked the phosphorylation of Smad2 (show SMAD2 Antibodies)/3, extracellular signal-regulated kinase (ERK (show EPHB2 Antibodies)) and Akt (show AKT1 Antibodies) in AML12 cells.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 3 (SMAD3) interaction partners

  1. the present work provides evidence supporting a functional role of SMAD2 (show SMAD2 Antibodies)/3 in bovine early embryogenesis

  2. Mechanical compression not only with physiological but also with excessive stress can activate Smad2 (show SMAD2 Antibodies)/3P signaling, which is known to be protective for articular cartilage and to block chondrocyte terminal differentiation.

  3. a detailed computational model for TGF-beta (show TGFB1 Antibodies) signalling that incorporates elements of previous models together with crosstalking between Smad1 (show SMAD1 Antibodies)/5/8 and Smad2 (show SMAD2 Antibodies)/3 channels through a negative feedback loop dependent on Smad7 (show SMAD7 Antibodies).

SMAD3 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Alternative names and synonyms associated with SMAD3

  • SMAD family member 3 (SMAD3) antibody
  • MAD homolog 3a (Drosophila) (smad3a) antibody
  • mothers against decapentaplegic homolog 3 (LOC100346303) antibody
  • SMAD family member 3 (smad3) antibody
  • SMAD family member 3 (Smad3) antibody
  • AU022421 antibody
  • HSPC193 antibody
  • HsT17436 antibody
  • JV15-2 antibody
  • LDS1C antibody
  • LDS3 antibody
  • mad3 antibody
  • Madh3 antibody
  • madh3-A antibody
  • madh3a antibody
  • Smad 3 antibody
  • smad3 antibody
  • wu:fa99e03 antibody
  • XenMLP antibody
  • Xmad3 antibody
  • XSmad3 antibody

Protein level used designations for SMAD3

MAD homolog 3 , MAD homolog 3a , MAD, mothers against decapentaplegic homolog 3 , SMA- and MAD-related protein 3 , SMAD, mothers against DPP homolog 3 , hMAD-3 , hSMAD3 , mad homolog JV15-2 , mad protein homolog , mad3 , mothers against DPP homolog 3 , mothers against decapentaplegic homolog 3 , SMAD 3 , TGF beta response effector Smad3 , TGF-beta response effector Smad3 , Smad 3 , mMad3 , MAD (mothers against decapentaplegic, Drosophila) homolog 3 , SMAD family member 3

100033845 Equus caballus
58092 Danio rerio
100346303 Oryctolagus cuniculus
4088 Homo sapiens
378633 Xenopus laevis
395132 Gallus gallus
610902 Canis lupus familiaris
397260 Sus scrofa
17127 Mus musculus
25631 Rattus norvegicus
515125 Bos taurus
100731807 Cavia porcellus
443169 Ovis aries
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