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EDNRB antibody (C-Term)
EDNRB
Reactivity: Human, Mouse
WB, FACS, IHC (p), IF
Host: Rabbit
Polyclonal
RB19285
unconjugated
Product Details anti-EDNRB Antibody
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Target
See all EDNRB Antibodies
EDNRB
(Endothelin Receptor Type B (EDNRB))
Binding Specificity
All epitopes for EDNRB antibodies
AA 409-439, C-Term
Reactivity
All reactivities for EDNRB antibodies
Human, Mouse
Host
All hosts for EDNRB antibodies
Rabbit
Clonality
All clonalities for EDNRB antibodies
Polyclonal
Conjugate
All conjugates for EDNRB antibodies
This EDNRB antibody is un-conjugated
Application
All applications for EDNRB antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Predicted Reactivity
B, Hs, Pig, Rb, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This EDNRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human EDNRB.
Clone
RB19285
Isotype
Ig Fraction
Alternatives
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Application Details
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Application Notes
IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for EDNRB
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Target
EDNRB
(Endothelin Receptor Type B (EDNRB))
Alternative Name
EDNRB (EDNRB Products )
Synonyms
ABCDS antibody, ET-B antibody, ET-BR antibody, ETB antibody, ETBR antibody, ETRB antibody, HSCR antibody, HSCR2 antibody, WS4A antibody, Ednra antibody, Etb antibody, ETR-b antibody, ETb antibody, Sox10m1 antibody, EDNRB antibody, abcds antibody, etb antibody, etrb antibody, hscr antibody, hscr2 antibody, endothelin receptor type B antibody, EDNRB antibody, Ednrb antibody, ednrb antibody
Background
EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
Molecular Weight
49644
Gene ID
1910
NCBI Accession
NP_000106 , NP_001116131 , NP_001188326 , NP_003982
UniProt
P24530
Pathways
Cellular Response to Molecule of Bacterial Origin , cAMP Metabolic Process
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