Browse our anti-ITPR1 (ITPR1) Antibodies

Full name:
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 Antibodies (ITPR1)
On are 62 Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) Antibodies from 17 different suppliers available. Additionally we are shipping ITPR1 Proteins (5) and ITPR1 Kits (1) and many more products for this protein. A total of 68 ITPR1 products are currently listed.
D6Pas2, ENSMUSG00000072853, Gm10429, I145TR, InsP3R, INSP3R1, IP3R, IP3R1, Itpr-1, opt, P400, Pcp-1, Pcp1, SCA15, SCA16, SCA29
list all antibodies Gene Name GeneID UniProt
ITPR1 16438 P11881
ITPR1 25262 P29994
ITPR1 3708 Q14643

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anti-Mouse (Murine) ITPR1 Antibodies:

anti-Rat (Rattus) ITPR1 Antibodies:

anti-Human ITPR1 Antibodies:

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Top referenced anti-ITPR1 Antibodies

  1. Human Polyclonal ITPR1 Primary Antibody for IHC, IHC (p) - ABIN4327442 : Klar, Hisatsune, Baig, Tariq, Johansson, Rasool, Malik, Ameur, Sugiura, Feuk, Mikoshiba, Dahl: Abolished InsP3R2 function inhibits sweat secretion in both humans and mice. in The Journal of clinical investigation 2014 (PubMed)

  2. Human Polyclonal ITPR1 Primary Antibody for ICC, IF - ABIN439358 : Wang, Li, Goode, Paz, Ouyang, Screaton, Fischer, Chen, Tabas, Montminy: Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. in Nature 2012 (PubMed)

  3. Human Monoclonal ITPR1 Primary Antibody for ELISA - ABIN561567 : Olson, Sandison, Chalmers, McCarron: Microdomains of muscarinic acetylcholine and Ins(1,4,5)P? receptors create 'Ins(1,4,5)P? junctions' and sites of Ca²+ wave initiation in smooth muscle. in Journal of cell science 2013 (PubMed)

More Antibodies against ITPR1 Interaction Partners

Mouse (Murine) Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) interaction partners

  1. Cone-specific gene deletion of the inositol-1,4,5-trisphosphate receptor type I (IP3R1) also significantly increased cone density in the CNG (show CNGA1 Antibodies)-channel-deficient mice, suggesting that IP3R1 signaling contributes to Ca(2 (show CA2 Antibodies)+) homeostasis and cone survival.

  2. Pathological mutations of ITPR1 (inositol 1,4,5-trisphosphate receptor, type 1) were found in seven patients from four families all localized in the IRBIT (show AHCYL1 Antibodies) (inositol triphosphate receptor binding protein) domain.

  3. The results suggest that IP3R1 and IP3R3 (show ITPR3 Antibodies) are required for extra-embryonic vascularization in the placenta, allantois, and yolk sac (show ADCY10 Antibodies).

  4. The results show that phosphorylations by Cdk1 (show CDK1 Antibodies) and MAPK (show MAPK1 Antibodies) enhance the activity of IP3R1, which is consistent with its maximal activity observed at the time of fertilization and the role of Ca(2 (show CA2 Antibodies)+) release in egg activation.

  5. data indicate that PTPalpha (show PTPRA Antibodies) and FAK (show PTK2 Antibodies), which are enriched in FAs (show FAS Antibodies), interact with IP3R1 at adjacent ER sites to spatially sequester IL-1 (show IL1A Antibodies)-induced Ca(2 (show CA2 Antibodies)+) signalling

  6. IGF-1 (show IGF1 Antibodies) strengthens the interaction between NCS-1 (show NCS1 Antibodies) and IP3R in the process of regulation of nuclear Ca2 (show CA2 Antibodies)+ signaling in cardiomyocytes.

  7. Car8 (show CA8 Antibodies) regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.

  8. cGMP/protein kinase (show CDK7 Antibodies) G signaling suppresses Itpr1 phosphorylation and promotes endoplasmic reticulum stress in photoreceptors of Cnga3 (show CNGA3 Antibodies)-deficient mice.

  9. Association of SLAT (show DEF6 Antibodies) with IP receptor 1 promotes Ca(2 (show CA2 Antibodies)) signaling in T cells.

  10. IP3R-mediated Ca2 (show CA2 Antibodies)+ signaling reinforces Tcf-1 (show HNF1A Antibodies) activity to both ensure normal development and to prevent thymocyte neoplasia.

Human Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) interaction partners

  1. Data suggest that ADRB2 (beta2 adrenergic receptor) activation (as illustrated by epinephrine and nor epinephrine) leads to robust calcium ion mobilization from intracellular stores in endoplasmic reticulum via activation of phosphoinositide phospholipase C (PLC) and opening of inositol trisphosphate receptor (IP3R).

  2. Data indicate that unlike ryanodine receptor RyRs, inositol 145-trisphosphate receptor IP3Rs are present and continually functional at early stages of cardiomyocyte differentiation.

  3. ITPR1 is the SCA15 causative gene.

  4. results demonstrate biallelic and monoallelic ITPR1 mutations as the underlying genetic defects for Gillespie syndrome, further extending the spectrum of ITPR1-related diseases

  5. Dominant De Novo ITPR1 Mutations Cause Gillespie Syndrome.

  6. Studies indicate that four IP3-binding sites within the tetrameric inositol 1,4,5-trisphosphate receptors (IP3Rs) must bind inositol 145-trisphosphate (IP3) before the channel can open for intracellular Ca2 (show CA2 Antibodies)+ signals.

  7. Data show that inositol 145-trisphosphate receptor type 1 (IP3R1) -with a single inositol 145-trisphosphate (IP3) binding-deficient subunit lack activity.

  8. SNPs in ITPR1 and CNTN4 (show CNTN4 Antibodies) are involved in the regulation of serum uric acid concentrations in Mexican Americans

  9. concluded that the HERPUD1 (show HERPUD1 Antibodies)-mediated cytoprotective effect against oxidative stress depends on the ITPR and Ca(2 (show CA2 Antibodies)+) transfer from the endoplasmic reticulum to mitochondria

  10. Studies indicate that the ryanodine receptors (RyRs: RyR1 (show RYR1 Antibodies), RyR2 (show RYR2 Antibodies), RyR3 (show RYR3 Antibodies)) and inositol 1,4,5-trisphosphate receptors (IP3Rs: IP3R1, IP3R2 (show ITPR2 Antibodies), IP3R3 (show ITPR3 Antibodies)) are the major Ca(2 (show CA2 Antibodies)+) release channels (CRCs) on the endo/sarcoplasmic reticulum (ER/SR).

Cow (Bovine) Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) interaction partners

  1. STIM1 (show STIM1 Antibodies) and STIM2 (show Stim2 Antibodies) are expressed in bovine aortic endothelial cells and they both interact with IP3R-1.

  2. we propose a model in which the partial unfolding of the suppressor domain by apo (show C9orf3 Antibodies)-CaM (show KRIT1 Antibodies) and the stepwise binding of the N lobe (show LTF Antibodies) of CaM (show KRIT1 Antibodies) to the suppressor domain are important elements of calcium/CaM (show KRIT1 Antibodies) inhibition of IP(3)R

  3. structural mapping of the amino acid sequences to several functional domains is deduced within the structure of the InsP3R1 tetramer

  4. the InsP3R/Ca2 (show CA2 Antibodies)+ channel is regulated by chromogranin B (show CHGB Antibodies)

  5. the redox potential and Ca(2 (show CA2 Antibodies)+) can regulate IP(3)R through totally different mechanisms: Ca(2 (show CA2 Antibodies)+) by the indirect effect and the redox potential by direct action causing conformational changes

ITPR1 Antigen Profile

Antigen Summary

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Alternative names and synonyms associated with ITPR1

  • inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1) antibody
  • inositol 1,4,5-trisphosphate receptor 1 (Itpr1) antibody
  • inositol 1,4,5-trisphosphate receptor, type 1 (Itpr1) antibody
  • D6Pas2 antibody
  • ENSMUSG00000072853 antibody
  • Gm10429 antibody
  • I145TR antibody
  • InsP3R antibody
  • INSP3R1 antibody
  • IP3R antibody
  • IP3R1 antibody
  • Itpr-1 antibody
  • opt antibody
  • P400 antibody
  • Pcp-1 antibody
  • Pcp1 antibody
  • SCA15 antibody
  • SCA16 antibody
  • SCA29 antibody

Protein level used designations for ITPR1

inositol 1,4,5-triphosphate receptor, type 1 , type I inositol triphosphate receptor , IP3 receptor , IP3R 1 , InsP3R type I , InsP>3

395412 Gallus gallus
476548 Canis lupus familiaris
100052808 Equus caballus
16438 Mus musculus
25262 Rattus norvegicus
3708 Homo sapiens
317697 Bos taurus
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