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anti-Human JAK3 antibody for ELISA

Recommended JAK3 Antibody (supplied by: Log in to see )

Antigen
Tyrosine-Protein Kinase JAK3 (JAK3) Antibodies
  • JAK-3
  • JAK3_HUMAN
  • JAKL
  • L-JAK
  • LJAK
  • fae
  • wil
  • RATJAK3
  • JAK
  • Janus kinase 3
  • JAK3
  • Jak3
Epitope
AA 1-620
17
17
15
15
10
8
7
7
4
3
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
87
61
43
2
2
2
2
2
1
Host
Mouse
66
24
1
Clonality
Monoclonal
Conjugate
This JAK3 antibody is un-conjugated
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
ELISA
52
37
27
14
12
11
9
7
4
3
1
1
1
Options
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Catalog No. ABIN393714
$ 450.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
10.891415 ABIN1327344 ELISA Mouse IgG2a kappa AA 1-619, full length Log in to see 1E10
10.891415 ABIN517291 ELISA Mouse IgG2a kappa AA 1-619, full length Log in to see 3F10
1 ABIN1532701 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 1
1 ABIN969224 ICC FACS ELISA WB Mouse IgG1 Log in to see 5H2 3
1 ABIN2869455 ELISA FACS ICC WB Mouse IgG1 Log in to see 5H2 3
1 ABIN1531677 IHC ELISA WB Rabbit IgG pTyr785 Log in to see Polyclonal
1 ABIN3182638 ELISA IHC WB Rabbit IgG pTyr785 Log in to see Polyclonal
1 ABIN3185259 ELISA IF IHC WB Rabbit IgG Ser645 Log in to see Polyclonal
1 ABIN393556 ELISA Mouse IgG2a kappa AA 1-620 Log in to see 2A5 5
1 ABIN517290 ELISA WB Mouse IgG2a kappa AA 1-619, full length Log in to see 2D5
1 ABIN4327888 ELISA FACS ICC IF WB Mouse IgG1 Log in to see 5H2
1 ABIN2293184 ELISA WB APC Rabbit IgG N-Term, AA 132-161 Log in to see Polyclonal
1 ABIN2293189 ELISA WB FITC Rabbit IgG N-Term, AA 132-161 Log in to see Polyclonal
1 ABIN2293178 FACS ELISA WB Mouse IgG1 Log in to see 13B433
1 ABIN2293193 ELISA WB PE Rabbit IgG N-Term, AA 132-161 Log in to see Polyclonal
1 ABIN2293191 ELISA WB HRP Rabbit IgG N-Term, AA 132-161 Log in to see Polyclonal
1 ABIN2293195 ELISA WB Rabbit IgG N-Term, AA 132-161 Log in to see Polyclonal
1 ABIN1844119 ELISA FACS IF/ICC WB Mouse IgG1 Log in to see
1 ABIN4901830 ELISA FACS IF WB Mouse IgG1 Log in to see 5H2
1 ABIN2293182 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG N-Term, AA 132-161 Log in to see Polyclonal

Top referenced anti-JAK3 antibody for ELISA

Similar anti-JAK3 Antibodies

Application / Reactivity Human
ELISA 37 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 11 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 6 Antibodies
Immunofluorescence (IF) 12 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 27 Antibodies
Immunohistochemistry (IHC) 12 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 49 Antibodies

General

Antigen Tyrosine-Protein Kinase JAK3 (JAK3) Antibodies
Epitope AA 1-620
(17), (17), (15), (15), (10), (8), (7), (7), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(87), (61), (43), (2), (2), (2), (2), (2), (1)
Host Mouse
(66), (24), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This JAK3 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application ELISA
(52), (37), (27), (14), (12), (11), (9), (7), (4), (3), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-JAK3 Antibody

Target Details JAK3 Application Details Handling References for anti-JAK3 Antibody (ABIN393714) Images
Specificity JAK3 (AAH28068, 1 a.a. ~ 620 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen JAK3 (AAH28068, 1 a.a. ~ 620 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3F10
Isotype IgG2a kappa

Target Details JAK3

Product Details anti-JAK3 Antibody Application Details Handling References for anti-JAK3 Antibody (ABIN393714) Images back to top
Antigen
Alternative Name JAK3 (JAK3 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 125099 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Pathways JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation

Application Details

Product Details anti-JAK3 Antibody Target Details JAK3 Handling References for anti-JAK3 Antibody (ABIN393714) Images back to top
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Restrictions For Research Use only

Handling

Product Details anti-JAK3 Antibody Target Details JAK3 Application Details References for anti-JAK3 Antibody (ABIN393714) Images back to top
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months

References for anti-JAK3 Antibody (ABIN393714)

Product Details anti-JAK3 Antibody Target Details JAK3 Application Details Handling Images back to top
Background publications

Kameda, Shide, Shimoda, Hidaka, Kubuki, Katayose, Taniguchi, Sekine, Kamiunntenn, Maeda, Nagata, Matsunaga, Shimoda: "Absence of gain-of-function JAK1 and JAK3 mutations in adult T cell leukemia/lymphoma." in: International journal of hematology, Vol. 92, Issue 2, pp. 320-5, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Lotz, Knutsen: "Janus kinase 3 missense mutation in a child with Jacobsen syndrome." in: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, Vol. 104, Issue 6, pp. 536-7, 2010

Chrencik, Patny, Leung, Korniski, Emmons, Hall, Weinberg, Gormley, Williams, Day, Hirsch, Kiefer, Leone, Fischer, Sommers, Huang, Jacobsen, Tenbrink, Tomasselli, Benson: "Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6." in: Journal of molecular biology, Vol. 400, Issue 3, pp. 413-33, 2010

Han, Lan, Park, Lee, Park, Ahn, Shin, Kang, Koo, Seo, Choi, Ahn, Chanock, Kim, Rothman, Kang: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010

Images

Product Details anti-JAK3 Antibody Target Details JAK3 Application Details Handling References for anti-JAK3 Antibody (ABIN393714) back to top
Supplier Images
ELISA image for anti-JAK3 antibody (Tyrosine-Protein Kinase JAK3) (AA 1-620) (ABIN393714) Detection limit for recombinant GST tagged JAK3 is approximately 3 ng/mL as a capture...