Browse our anti-MAP2K6 (MAP2K6) Antibodies

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 6 Antibodies (MAP2K6)
On are 215 Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) Antibodies from 27 different suppliers available. Additionally we are shipping MAP2K6 Kits (22) and MAP2K6 Proteins (18) and many more products for this protein. A total of 270 MAP2K6 products are currently listed.
list all antibodies Gene Name GeneID UniProt
MAP2K6 5608 P52564
MAP2K6 114495  
MAP2K6 26399 P70236

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Top referenced anti-MAP2K6 Antibodies

  1. Human Monoclonal MAP2K6 Primary Antibody for IF, WB - ABIN393607 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 393607

  2. Human Polyclonal MAP2K6 Primary Antibody for IF, IHC (p) - ABIN197354 : Wang, Chen, Liao, Deng, Zhou, Huang, Sun: Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. in Molecular and cellular biology 2002 (PubMed)
    Show all 2 references for 197354

  3. Human Polyclonal MAP2K6 Primary Antibody for IF, IHC (p) - ABIN196864 : Raingeaud, Whitmarsh, Barrett, Dérijard, Davis: MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. in Molecular and cellular biology 1996 (PubMed)
    Show all 2 references for 196864

  4. Human Monoclonal MAP2K6 Primary Antibody for IHC, ELISA - ABIN969270 : Arning, Monté, Hansen, Wieczorek, Jagiello, Akkad, Andrich, Kraus, Saft, Epplen: ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease. in Journal of molecular medicine (Berlin, Germany) 2008 (PubMed)

  5. Human Polyclonal MAP2K6 Primary Antibody for IF (p), IHC (p) - ABIN681568 : Shi, Zhan, Zhao, Wang, Ma: Effects of Fluoride on the Expression of p38MAPK Signaling Pathway-Related Genes and Proteins in Spleen Lymphocytes of Mice. in Biological trace element research 2016 (PubMed)

More Antibodies against MAP2K6 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) interaction partners

  1. Data indicate that mitogen-activated protein kinase kinase 6 (MKK6) levels were substantially higher in monocytes than in neutrophils.

  2. Data show significant increase in the expression of MKK6 in Esophageal, Stomach, and Colon cancers as compared to controls.

  3. uncover a new mechanism of deactivation of MKK6-p38 (show CRK Antibodies) and substantiate a novel regulatory role of FBXO31 (show FBXO5 Antibodies) in stress response

  4. Serine phosphorylation of p66shc (show SHC1 Antibodies) is carried out by active MKK6. beta-Amyloid-induced ROS (show ROS1 Antibodies) production and apoptosis increased in the presence of MKK6 and p66shc (show SHC1 Antibodies), which directly associate.

  5. The models confirmed the reaction order, revealed processivity in the phosphorylation of MEK6 by ASK1 (show MAP3K5 Antibodies), and suggested that the order of phosphorylation is dictated by both binding and catalysis rates.

  6. crystal structure of human non-phosphorylated MAP2K6 (npMAP2K6) complexed with an ATP analogue was determined at 2.6 A resolution and represents an auto-inhibition state of MAP2K6

  7. Data suggest aberrant MAP2K protein (MKK3 (show MAP2K3 Antibodies), MKK4 (show MAP2K4 Antibodies), MKK6, and MKK7 (show MAP2K7 Antibodies)) expression indicates that altered cellular signal transduction mediated via JNK (show MAPK8 Antibodies) and p38 (show CRK Antibodies) may be common in bladder cancer.

  8. the balance between MKK6 and MKK3 (show MAP2K3 Antibodies) mediates p38 MAPK (show MAPK14 Antibodies) associated resistance to cisplatin in NSCLC

  9. activation by mechanical stretch induces HMGB1 (show HMGB1 Antibodies) and cytokine expression in A549 cells

  10. Results suggest that the p38alpha (show MAPK14 Antibodies), MAPK (show MAPK1 Antibodies), and MKK6 play prominent roles in IL-1beta (show IL1B Antibodies) and C/EBP-beta (show CEBPB Antibodies)-mediated C3 gene expression in astrocytes.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) interaction partners

  1. MKK3 (show MAP2K3 Antibodies) and MKK6 differentially regulate bone loss due to estrogen withdrawal. MKK3 (show MAP2K3 Antibodies) directly mediates osteoclastogenesis while MKK6 likely contributes to pro-inflammatory cytokine production that promotes osteoclast formation.

  2. Activation of distinct p38MAPK (show MAPK14 Antibodies) isoforms is regulated by the selective and synchronized action of two kinases, MKK3 (show MAP2K3 Antibodies) and MKK6, in response to cell stress.

  3. MKK6 is downreglated in peripheral CD4 (show CD4 Antibodies)(+)T cells

  4. p38alpha (show MAPK14 Antibodies) can negatively regulate the stability of the MKK6 mRNA and thus control the steady-state concentration of one of its upstream activators

  5. Involvement of MKK6 in apoptotic cell death in thymocytes.

  6. MKK6 is one of three different protein kinases which activate p38 MAPK (show MAPK14 Antibodies) in vitro.

  7. MKK3 (show MAP2K3 Antibodies) and MKK6 are rapidly activated during engagement of the Type I IFN receptor and play important roles in Type I IFN signaling and the generation of IFN responses

  8. increased activity of Sox9 (show SOX9 Antibodies) accounts at least in part for the phenotype caused by constitutive activation of MKK6 in chondrocytes

  9. These results indicate that TAK1 (show NR2C2 Antibodies) and MKK6 constitute the p38 (show CRK Antibodies) signalling pathway to participate to Oc differentiation by RANKL (show TNFSF11 Antibodies) through p65 (show NFkBP65 Antibodies) phosphorylation and NFATc1 (show NFATC1 Antibodies) induction.

  10. All these results suggest that DGK (show DGUOK Antibodies) may play a role in glucose transport in the skeletal muscle cells through modulating a MKK3 (show MAP2K3 Antibodies)/6-p38 (show CRK Antibodies) signaling pathway.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) interaction partners

  1. Arabidopsis MPK4 (show MAPK4 Antibodies) can interact with and be phosphorylated by the cytokinesis-related MAP kinase (show MAPK1 Antibodies) kinase, AtMKK6.

  2. AtMKK6-AtMPK13 (show MAPK1/3 Antibodies) module positively regulates lateral root formation.

  3. Plants with mutations in the MKK6/ANQ gene exhibit severe defects in cytokinesis.

MAP2K6 Antigen Profile

Antigen Summary

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Alternative names and synonyms associated with MAP2K6

  • mitogen-activated protein kinase kinase 6 (MAP2K6) antibody
  • mitogen-activated protein kinase kinase 6 (Map2k6) antibody
  • mitogen-activated protein kinase kinase 6 (MKK6) antibody
  • mitogen-activated protein kinase kinase 6 (map2k6) antibody
  • ANQ1 antibody
  • ARABIDOPSIS NQK1 antibody
  • ATMKK6 antibody
  • map2k3 antibody
  • MAP kinase kinase 6 antibody
  • MAPKK6 antibody
  • MEK6 antibody
  • MIK19.2 antibody
  • MIK19_2 antibody
  • MKK3 antibody
  • Mkk6 antibody
  • Prkmk6 antibody
  • SAPKK-3 antibody
  • SAPKK3 antibody
  • zMKK3 antibody

Protein level used designations for MAP2K6

MAPK/ERK kinase 6 , MAPKK 6 , MEK 6 , SAPK kinase 3 , dual specificity mitogen-activated protein kinase kinase 6 , protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6) , stress-activated protein kinase kinase 3 , MAP kinase kinase 6 , mitogen activated protein kinase kinase 6 , protein kinase, mitogen activated, kinase 6 , mitogen-activated protein kinase kinase 3

5608 Homo sapiens
114495 Rattus norvegicus
26399 Mus musculus
286883 Bos taurus
417445 Gallus gallus
100355230 Oryctolagus cuniculus
100731419 Cavia porcellus
835759 Arabidopsis thaliana
65239 Danio rerio
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