anti-Rat (Rattus) MAP3K11 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended MAP3K11 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) Antibodies
  • MEKK11
  • MLK-3
  • MLK3
  • PTK1
  • SPRK
  • 2610017K16Rik
  • Mlk3
  • Mlk-3
  • RHOE
  • mitogen-activated protein kinase kinase kinase 11
  • MAP3K11
  • Map3k11
Epitope
pThr277, pSer281, AA 260-300
10
4
3
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
61
32
22
2
2
2
2
2
2
1
1
Host
Rabbit
49
11
Clonality
Polyclonal
Conjugate
This MAP3K11 antibody is un-conjugated
2
2
2
2
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
54
32
10
3
2
1
1
1
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Catalog No. ABIN743963
$ 317.90
Plus shipping costs $45.00

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) Antibodies
Epitope pThr277, pSer281, AA 260-300
(10), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(61), (32), (22), (2), (2), (2), (2), (2), (2), (1), (1)
Host Rabbit
(49), (11)
Clonality
Polyclonal
Conjugate This MAP3K11 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(54), (32), (10), (3), (2), (1), (1), (1)
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Product Details anti-MAP3K11 Antibody

Target Details MAP3K11 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human MLK3 around the phosphorylation site of Thr277/Ser281
Isotype IgG

Target Details MAP3K11

Product Details anti-MAP3K11 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Mlk3 (MAP3K11 Antibody Abstract)
Background

Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Subcellular location: Cytoplasm

Synonyms: MLK3, PTK1, SPRK, MLK-3, MEKK11, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11

Gene ID 4296
UniProt Q16584
Research Area Signaling, Tyrosine Kinases
Pathways MAPK Signaling, Interferon-gamma Pathway

Application Details

Product Details anti-MAP3K11 Antibody Target Details MAP3K11 Handling Images back to top
Application Notes IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-MAP3K11 Antibody Target Details MAP3K11 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-MAP3K11 Antibody Target Details MAP3K11 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (AA 260-300), (pSer281), (pThr277) antibody (ABIN743963) Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti Phosph...
Immunofluorescence (IF) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (AA 260-300), (pSer281), (pThr277) antibody (ABIN743963) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti Phospho-M...