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anti-Human IL1R1 antibody for ELISA

Recommended IL1R1 Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 Receptor, Type I (IL1R1) Antibodies
  • CD121A
  • D2S1473
  • IL-1R-alpha
  • IL1R
  • IL1RA
  • P80
  • CD121a
  • CD121b
  • IL-iR
  • Il1r-1
  • interleukin 1 receptor, type I
  • IL1R1
  • Il1r1
Epitope
AA 1-332
31
20
15
9
6
6
6
5
5
5
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
108
63
24
2
1
1
Host
Rabbit
108
33
26
18
2
1
Clonality
Polyclonal
Conjugate
This IL1R1 antibody is un-conjugated
12
10
8
7
4
4
1
1
1
1
Application
ELISA, Western Blotting (WB)
107
90
44
42
29
15
10
8
5
5
4
4
2
2
2
2
2
2
1
1
1
1
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Catalog No. ABIN1995763
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1995759 ELISA Mouse IgG2b AA 1-332 Log in to see 9A2B1C3 1
1 ABIN1995761 ELISA Rabbit IgG AA 1-332 Log in to see Polyclonal 1
1 ABIN2466931 RIA IHC ELISA Mouse IgG2b Extracellular Domain Log in to see 40101
1 ABIN4880786 ELISA FACS WB Mouse IgG1 AA 18-167 Log in to see 4D2D12
1 ABIN1723174 IHC (p) RIA ELISA Mouse IgG2b Extracellular Domain Log in to see 40101
1 ABIN364253 IHC (p) RIA ELISA Mouse IgG2b Extracellular Domain Log in to see 40101
1 ABIN1905024 ELISA WB APC Rabbit IgG C-Term, AA 421-450 Log in to see Polyclonal
1 ABIN1905026 ELISA WB FITC Rabbit IgG C-Term, AA 421-450 Log in to see Polyclonal
1 ABIN1905027 ELISA WB PE Rabbit IgG C-Term, AA 421-450 Log in to see Polyclonal
1 ABIN1905025 ELISA WB Biotin Rabbit IgG C-Term, AA 421-450 Log in to see Polyclonal
1 ABIN1905023 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG C-Term, AA 421-450 Log in to see Polyclonal
1 ABIN3031431 IHC ELISA WB Rabbit Ig Fraction AA 474-503 Log in to see Polyclonal
1 ABIN2623994 ELISA Rabbit IgG AA 421-450 Log in to see Polyclonal
1 ABIN1905022 ELISA WB HRP Rabbit IgG C-Term, AA 421-450 Log in to see Polyclonal
1 ABIN799832 IP RIA ELISA Rabbit Extracellular Domain Log in to see Polyclonal
1 ABIN967343 ELISA WB Mouse IgG1, kappa Log in to see hIL1R-M1 5
1 ABIN3031430 ELISA WB Rabbit Ig Fraction AA 422-450 Log in to see Polyclonal
1 ABIN470897 IP RIA ELISA Rabbit Extracellular Domain Log in to see Polyclonal
1 ABIN561452 ELISA WB Mouse AA 18-127, partial Log in to see Polyclonal
1 ABIN1953219 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Tyr496, pTyr496 Log in to see Polyclonal

Top referenced anti-IL1R1 antibody for ELISA

Similar anti-IL1R1 Antibodies

Application / Reactivity Human
ELISA 68 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 5 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 3 Antibodies
Immunohistochemistry (IHC) 37 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies
Immunoprecipitation (IP) 9 Antibodies
Radioimmunoassay (RIA) 15 Antibodies
Western Blotting (WB) 71 Antibodies

General

Antigen Interleukin 1 Receptor, Type I (IL1R1) Antibodies
Epitope AA 1-332
(31), (20), (15), (9), (6), (6), (6), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(108), (63), (24), (2), (1), (1)
Host Rabbit
(108), (33), (26), (18), (2), (1)
Clonality
Polyclonal
Conjugate This IL1R1 antibody is un-conjugated
(12), (10), (8), (7), (4), (4), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(107), (90), (44), (42), (29), (15), (10), (8), (5), (5), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-IL1R1 Antibody

Target Details IL1R1 Application Details Handling References for anti-IL1R1 Antibody (ABIN1995763) Images
Specificity Human IL1R1 / CD121a
Sensitivity 0.00245 ng/well
Characteristics Produced in rabbits immunized with purified, recombinant Human IL1R1 (rh IL1R1, NP_000868.1, Met 1-Thr 332). IL1R1 specific IgG was purified by human IL1R1 affinity chromatography.
Purification Affinity Purified
Sterility 0.2 μm filtered
Isotype IgG

Target Details IL1R1

Product Details anti-IL1R1 Antibody Application Details Handling References for anti-IL1R1 Antibody (ABIN1995763) Images back to top
Antigen
Alternative Name IL1R1 (IL1R1 Antibody Abstract)
Background Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA). IL-1R1/CD121a is an important mediator involved in many cytokine induced immune and inflammatory responses. This protein has been characterized by pharmacological and molecular techniques in the mouse brain. The spindle-shaped astrocytes enclose the wound, separating the healthy from damaged neural tissue. The shape change and subsequent repair processes are IL-1β activity-dependent, acting through the IL-1 type 1 receptor (IL-1R1), as co-application of the IL-1type 1 receptor antagonist protein (IL-1ra) blocks IL-1β induced effects. In the spleen, a slight increase in IL-1R AcP and IL-1R1 was observed during the first hours following LPS stimulation. In conclusion, IL-1R AcP mRNA is expressed in the brain and in other tissues where IL-1R1/CD121a transcripts are found. However, the regulation of its expression is distinct from IL-1R1/CD121a. The high level of expression and the lack of regulation of IL-1R AcP transcripts in the brain under inflammatory conditions suggest that the protein might be constitutively expressed in excess.
NCBI Accession NP_000868.1
Research Area Immunology
Pathways NF-kappaB Signaling

Application Details

Product Details anti-IL1R1 Antibody Target Details IL1R1 Handling References for anti-IL1R1 Antibody (ABIN1995763) Images back to top
Application Notes ELISA ELISA: 0.5-1.0 μg/mL This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human IL1R1. The detection limit for Human IL1R1 is 0.00245 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-IL1R1 Antibody Target Details IL1R1 Application Details References for anti-IL1R1 Antibody (ABIN1995763) Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months

References for anti-IL1R1 Antibody (ABIN1995763)

Product Details anti-IL1R1 Antibody Target Details IL1R1 Application Details Handling Images back to top
Background publications

Vigers, Anderson, Caffes, Brandhuber: "Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta." in: Nature, Vol. 386, Issue 6621, pp. 190-4, 1997

Images

Product Details anti-IL1R1 Antibody Target Details IL1R1 Application Details Handling References for anti-IL1R1 Antibody (ABIN1995763) back to top
Supplier Images
Western Blotting (WB) image for anti-IL1R1 antibody (Interleukin 1 Receptor, Type I) (AA 1-332) (ABIN1995763) anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 1-332) antibody
Immunoprecipitation (IP) image for anti-IL1R1 antibody (Interleukin 1 Receptor, Type I) (AA 1-332) (ABIN1995763) anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 1-332) antibody (Image 2)