Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) Antibodies
This IRAK1 antibody is un-conjugated
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
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Antigen affinity purified
A portion of amino acids 405-433 from the mouse protein was used as the immunogen for this Irak1 antibody.
IRAK1 Antibody Abstract)
Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.
NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Titration of the Irak1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
For Research Use only
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Aliquot the Irak1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Irak1 antibody flow cytometric analysis of Neuro-2a cells (right histogram) compared ...
Irak1 antibody western blot analysis in mouse Neuro-2a lysate.