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Browse our TNFRSF1A Proteins (TNFRSF1A)

Full name:
Tumor Necrosis Factor Receptor Superfamily, Member 1A Proteins (TNFRSF1A)
On www.antibodies-online.com are 67 Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Proteins from 17 different suppliers available. Additionally we are shipping TNFRSF1A Antibodies (441) and TNFRSF1A Kits (77) and many more products for this protein. A total of 610 TNFRSF1A products are currently listed.
Synonyms:
CD120a, FPF, MS5, p55, p55-R, p60, TBP1, TNF-alphaR1, TNF-R, TNF-R-I, TNF-R1, TNF-R55, TNFalpha-R1, TNFAR, Tnfr-2, Tnfr1, TNFR1-d2, TNFR55, TNFR60, TNFR I, TNFRI, TNFRp55, TNFRSF1A, wu:fj65b10, xtnfr1, zgc:85914
list all proteins Gene Name GeneID UniProt
TNFRSF1A 7132 P19438
TNFRSF1A 21937 P25118
TNFRSF1A 25625 P22934

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TNFRSF1A Proteins (TNFRSF1A) by Origin

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Top referenced TNFRSF1A Proteins

  1. Human TNFRSF1A Protein expressed in Escherichia coli (E. coli) - ABIN1047844 : Gray, Barrett, Chantry, Turner, Feldmann: Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 5 references for ABIN1047844

  2. Human TNFRSF1A Protein expressed in Human Cells - ABIN2003515 : Banner, DArcy, Janes, Gentz, Schoenfeld, Broger, Loetscher, Lesslauer: Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. in Cell 1993 (PubMed)
    Show all 5 references for ABIN2003515

  3. Mouse (Murine) TNFRSF1A Protein expressed in Human Cells - ABIN2007895 : Chan, Chun, Zheng, Siegel, Bui, Lenardo: A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. in Science (New York, N.Y.) 2000 (PubMed)
    Show all 5 references for ABIN2007895

  4. Rat (Rattus) TNFRSF1A Protein expressed in Human Cells - ABIN2009259 : Lewis, Tartaglia, Lee, Bennett, Rice, Wong, Chen, Goeddel: Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 5 references for ABIN2009259

  5. Human TNFRSF1A Protein expressed in HEK-293 Cells - ABIN2181839 : Jiang, Woronicz, Liu, Goeddel: Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 3 references for ABIN2181839

  6. Human TNFRSF1A Protein expressed in Escherichia coli (E. coli) - ABIN1098686 : Dunbar, Song, Guo, Wu, Donner: Two-hybrid cloning of a gene encoding TNF receptor-associated protein 2, a protein that interacts with the intracellular domain of the type 1 TNF receptor: identity with subunit 2 of the 26S protease. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
    Show all 2 references for ABIN1098686

More Proteins for TNFRSF1A Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. These results strongly indicate that anti-inflammatory effects in TNF-alpha (show TNF Proteins)-stimulated endothelial cells by acetylation are tightly linked to secreted APE1/Ref-1 (show APEX1 Proteins), which inhibits TNF-alpha (show TNF Proteins) binding to TNFR1 by reductive conformational change, with suggestion as an endogenous inhibitor of vascular inflammation.

  2. Results suggest that miR (show MLXIP Proteins)-29a is an important regulator of tumor necrosis factor receptor 1 expression in breast cancer and functions as a tumor suppressor by targeting tumor necrosis factor receptor 1 to influence the growth of MCF-7 cell.

  3. SCCAg, CYFRA 21.1, IL-6, VEGF and sTNF receptors have roles in squamous cell cervical cancer

  4. In chronic inflammatory demyelinating polyradiculoneuropathy patients, transcriptome analysis showed that the TNFR1 pathway was significantly lessened by intravenous immunoglobulins . TNF-alpha (show TNF Proteins) gene expression was higher in responder patients than in nonresponders; however, it decreased after intravenous immunoglobulins in responders, but remained stable in nonresponders.

  5. link between miRNAs and the TNF (show TNF Proteins)/TNFR superfamily is especially exciting. Understanding the molecular basis of these links in future studies may pave the way for using these miRNAs as therapeutic targets in CLL

  6. The TNFR1 gene contains a polymorphism that replaced an adenine with a cytosine at the -383 in promoter region position. We examined the association between the TNFR1-383 A>C polymorphism and TNFR1 soluble (sTNFR1) levels and laboratory and clinical characteristics in primary Sjogren's syndrome patients.

  7. tumor necrosis factor receptor superfamily member 1A is significantly higher in serum of endometriosis patients than controls

  8. The serum levels of TNF-alpha (show TNF Proteins) and sTNFR I showed a significant decreasing trend after treatment in cutaneous leishmaniasis.

  9. These results suggest that CR1 induces apoptosis by activating the caspase (show CASP3 Proteins) pathway via binding to TNFR1.

  10. Following TNF (show TNF Proteins)-converting enzyme-mediated ectodomain shedding of TNF (show TNF Proteins) type I receptor (TNFR1), the membrane-bound TNFR1 C-terminal fragment is subsequently cleaved by gamma-secretase to generate a cytosolic TNFR1 intracellular domain.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. Data, including data from studies in knockout mice, suggest that TNF (tumor necrosis factor (show TNF Proteins)), TNFR1 (TNF (show TNF Proteins) receptor 1), and IL18 (interleukin 18 (show IL18 Proteins)) are involved in liver lipid metabolism. IL18 (show IL18 Proteins) or TNFR1 knockout mice on chow show higher liver triglyceride deposition than wild-type mice fed chow; in IL18 (show IL18 Proteins) or TNFR1 knockout mice, high-refined-carbohydrate diet does not lead to fatty liver disease as it does in wild-type mice.

  2. Knockdown of TNFR1 not only inhibited the JNK (show MAPK8 Proteins) pathway but also reduced Toll-like receptor 2 protein and RANKL (show TNFSF11 Proteins) levels in S. aureus-infected cells.

  3. we have demonstrated that PGRN (show GRN Proteins)-mediated inhibition of chemokine (show CCL1 Proteins) expression largely depends on TNFR1.

  4. The results of comparative analysis of interaction between the protein cytotoxic complex Tag 7 (show PGLYRP1 Proteins)-Hsp70 (show HSP70 Proteins) and the Tag 7 (show PGLYRP1 Proteins) component of this complex with TNFR1 receptor in solution and in tumor cells are presented.

  5. These results show that in the absence of TNFRp55, Leishmania (Leishmania) amazonensis-infected knockout mice fail to resolve lesions, whereas wild-type mice completely heal.

  6. These findings implicate TNF (show TNF Proteins)-receptor signaling cascades in the regulation of homeostatic plasticity of denervated networks and suggest an important role for TNFalpha (show TNF Proteins)-signaling in the course of neurological diseases accompanied by deafferentation.

  7. DMS5540 is a potent mouse TNFR1 antagonist with in vivo pharmacokinetic

  8. Knockdown of sTNFR1 in S-MSCs decreased their inhibitory effect on Th17 cell differentiation ex vivo and in vivo. Thus, our data identified sTNFR1 and its target TNF-a (show TNF Proteins) as critical regulators for Th17 cell differentiation

  9. TNF (show TNF Proteins) receptor 1 (TnfR1) signaling is believed to be a major mediator of the cytotoxicity of Tnf-a (show TNF Proteins) through activation of caspases.

  10. The authors found that miR (show MLXIP Proteins)-511 inhibits endotoxemia and experimental hepatitis and that this miR (show MLXIP Proteins) is strongly induced by glucocorticoids and is a true TNFR1 modulator and thus an anti-inflammatory miR (show MLXIP Proteins).

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. Retinal ischemia results in increased expression of TNF-alpha (show TNF Proteins) and its receptors (TNF-R1 and TNF-R2 (show TNFRSF1B Proteins)).

Cow (Bovine) Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. These results suggest that TNF-alpha (show TNF Proteins) sources include immune cells, as well as large and small luteal cells, and that TNF-RI and TNF-RII (show TNFRSF1B Proteins) are present in the luteal cells of the bovine corpus luteum.

  2. The expression and cellular localization of tumor necrosis factor-alpha (TNF (show TNF Proteins)) and its receptors (TNFRI and TNFRII (show TNFRSF1B Proteins)) mRNAs and proteins, were determined.

  3. The upregulation of TNFRI mRNA expression by IFNG (show IFNG Proteins) suggests that TNF (show TNF Proteins) and IFNG (show IFNG Proteins) synergistically affect the death of luteal endothelial cells resulting in acute luteolysis

  4. TNF (show TNF Proteins) binding induces release of AIP1 (DAB2IP (show DAB2IP Proteins)) from TNFR1, resulting in cytoplasmic translocation and concomitant formation of an intracellular signaling complex comprised of TRADD (show TRADD Proteins), RIP1 (show RALBP1 Proteins), TRAF2 (show TRAF2 Proteins), and AIPl.

Zebrafish Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. Targeted gene knockdown of TNFRSF1B (show TNFRSF1B Proteins) in zebrafish embryos results in the induction of a caspase-8 (show CASP8 Proteins), caspase-2 (show CASP2 Proteins) and P53 (show TP53 Proteins)-dependent apoptotic program in endothelial cells that bypasses caspase-3 (show CASP3 Proteins).

TNFRSF1A Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.

Alternative names and synonyms associated with TNFRSF1A

  • tumor necrosis factor receptor superfamily, member 1A (tnfrsf1a)
  • tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A)
  • tumor necrosis factor receptor superfamily, member 1a (Tnfrsf1a)
  • tumor necrosis factor receptor superfamily, member 1A (Tnfrsf1a)
  • tumor necrosis factor receptor superfamily, member 1a (tnfrsf1a)
  • CD120a protein
  • FPF protein
  • MS5 protein
  • p55 protein
  • p55-R protein
  • p60 protein
  • TBP1 protein
  • TNF-alphaR1 protein
  • TNF-R protein
  • TNF-R-I protein
  • TNF-R1 protein
  • TNF-R55 protein
  • TNFalpha-R1 protein
  • TNFAR protein
  • Tnfr-2 protein
  • Tnfr1 protein
  • TNFR1-d2 protein
  • TNFR55 protein
  • TNFR60 protein
  • TNFR I protein
  • TNFRI protein
  • TNFRp55 protein
  • TNFRSF1A protein
  • wu:fj65b10 protein
  • xtnfr1 protein
  • zgc:85914 protein

Protein level used designations for TNFRSF1A

tumor necrosis factor receptor 1 , tumor necrosis factor receptor p60 , tumor necrosis factor receptor superfamily member 1A , tumor necrosis factor type I , tumor necrosis factor receptor superfamily, member 1A , tumor necrosis factor receptor superfamily member 1A-like , TNF-R1 , TNF-RI , TNFR-I , tumor necrosis factor binding protein 1 , tumor necrosis factor receptor 1A isoform beta , tumor necrosis factor receptor type 1 , tumor necrosis factor-alpha receptor , TNF receptor alpha chain , TNF-alpha-R1 , p60 , tumor necrosis factor receptor type I , p55 , p55 TNF receptor , TNF Receptor 1 (TR1) , TNFR1

GENE ID SPECIES
100137626 Xenopus laevis
100144930 Xenopus (Silurana) tropicalis
403634 Canis lupus familiaris
466934 Pan troglodytes
493957 Felis catus
722033 Macaca mulatta
100059548 Equus caballus
100135698 Ovis aries
100397418 Callithrix jacchus
7132 Homo sapiens
21937 Mus musculus
25625 Rattus norvegicus
397020 Sus scrofa
282527 Bos taurus
418325 Gallus gallus
100713890 Cavia porcellus
406471 Danio rerio
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