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Browse our TNFRSF1A Proteins (TNFRSF1A)

Full name:
Tumor Necrosis Factor Receptor Superfamily, Member 1A Proteins (TNFRSF1A)
On www.antibodies-online.com are 65 Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Proteins from 16 different suppliers available. Additionally we are shipping TNFRSF1A Antibodies (387) and TNFRSF1A Kits (80) and many more products for this protein. A total of 559 TNFRSF1A products are currently listed.
Synonyms:
CD120a, FPF, MS5, p55, p55-R, p60, TBP1, TNF-alphaR1, TNF-R, TNF-R-I, TNF-R1, TNF-R55, TNFalpha-R1, TNFAR, Tnfr-2, Tnfr1, TNFR1-d2, TNFR55, TNFR60, TNFR I, TNFRI, TNFRp55, TNFRSF1A, wu:fj65b10, xtnfr1, zgc:85914
list all proteins Gene Name GeneID UniProt
TNFRSF1A 7132 P19438
TNFRSF1A 21937 P25118
TNFRSF1A 25625 P22934

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TNFRSF1A Proteins (TNFRSF1A) by Origin

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Top referenced TNFRSF1A Proteins

  1. Human TNFRSF1A Protein expressed in Escherichia coli (E. coli) - ABIN1047844 : Gray, Barrett, Chantry, Turner, Feldmann: Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 5 references for ABIN1047844

  2. Human TNFRSF1A Protein expressed in Human Cells - ABIN2003513 : Banner, DArcy, Janes, Gentz, Schoenfeld, Broger, Loetscher, Lesslauer: Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. in Cell 1993 (PubMed)
    Show all 5 references for ABIN2003513

  3. Mouse (Murine) TNFRSF1A Protein expressed in Human Cells - ABIN2007897 : Chan, Chun, Zheng, Siegel, Bui, Lenardo: A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. in Science (New York, N.Y.) 2000 (PubMed)
    Show all 5 references for ABIN2007897

  4. Rat (Rattus) TNFRSF1A Protein expressed in Human Cells - ABIN2009259 : Lewis, Tartaglia, Lee, Bennett, Rice, Wong, Chen, Goeddel: Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 5 references for ABIN2009259

  5. Human TNFRSF1A Protein expressed in HEK-293 Cells - ABIN2181837 : Jiang, Woronicz, Liu, Goeddel: Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 3 references for ABIN2181837

  6. Human TNFRSF1A Protein expressed in Escherichia coli (E. coli) - ABIN1098686 : Dunbar, Song, Guo, Wu, Donner: Two-hybrid cloning of a gene encoding TNF receptor-associated protein 2, a protein that interacts with the intracellular domain of the type 1 TNF receptor: identity with subunit 2 of the 26S protease. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
    Show all 2 references for ABIN1098686

More Proteins for TNFRSF1A Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. The serum levels of TNF-alpha (show TNF Proteins) and sTNFR I showed a significant decreasing trend after treatment in cutaneous leishmaniasis.

  2. These results suggest that CR1 induces apoptosis by activating the caspase (show CASP3 Proteins) pathway via binding to TNFR1.

  3. Following TNF (show TNF Proteins)-converting enzyme-mediated ectodomain shedding of TNF (show TNF Proteins) type I receptor (TNFR1), the membrane-bound TNFR1 C-terminal fragment is subsequently cleaved by gamma-secretase to generate a cytosolic TNFR1 intracellular domain.

  4. TNFR1 (and IL-6 (show IL6 Proteins)) concentrations predict risk of recurrent vascular events in recent lacunar stroke patients.

  5. Tumor necrosis factor-alpha (show TNF Proteins) genetic polymorphism is not a genetic risk factor for developing vitiligo (show MITF Proteins).

  6. data suggest that the R92Q mutation gives rise to a stronger interaction between the receptor and its ligand, which results in the potentiation of TNF (show TNF Proteins)-mediated pathways

  7. Atorvastatin reduced soluble TNFR1/2 receptors in systemic lupus erythematosus.

  8. TNFR1 and TNFR2 were significant predictors of disease progression in IgA nephropathy.

  9. These results support further exploring the use of TNFR1-selective inhibition in inflammatory bone loss disorders such as osteomyelitis and peri (show PLIN1 Proteins)-prosthetic aseptic loosening.

  10. T. vaginalis Infection Is Associated with Increased IL-8 (show IL8 Proteins) and TNFr1 Levels

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. These findings implicate TNF (show TNF Proteins)-receptor signaling cascades in the regulation of homeostatic plasticity of denervated networks and suggest an important role for TNFalpha (show TNF Proteins)-signaling in the course of neurological diseases accompanied by deafferentation.

  2. DMS5540 is a potent mouse TNFR1 antagonist with in vivo pharmacokinetic

  3. Knockdown of sTNFR1 in S-MSCs decreased their inhibitory effect on Th17 cell differentiation ex vivo and in vivo. Thus, our data identified sTNFR1 and its target TNF-a (show TNF Proteins) as critical regulators for Th17 cell differentiation

  4. TNF (show TNF Proteins) receptor 1 (TnfR1) signaling is believed to be a major mediator of the cytotoxicity of Tnf-a (show TNF Proteins) through activation of caspases.

  5. The authors found that miR (show MLXIP Proteins)-511 inhibits endotoxemia and experimental hepatitis and that this miR (show MLXIP Proteins) is strongly induced by glucocorticoids and is a true TNFR1 modulator and thus an anti-inflammatory miR (show MLXIP Proteins).

  6. Data show that ileal sections were costained for glucagon-like peptide-1 (GLP-1 (show GCG Proteins)) and tumor necrosis factor (show TNF Proteins) receptor TNFR1.

  7. ACE2 (show ACE2 Proteins) deficiency exacerbates kidney inflammation, oxidative stress and adverse renal injury in the ApoE (show APOE Proteins)-mutant mice through modulation of the nephrin (show NPHS1 Proteins), NOX4 (show NOX4 Proteins) and TNF-alpha (show TNF Proteins)-TNFRSF1A signaling.

  8. quercetin reduces cell survival and promotes death receptor-mediated apoptosis via differential localization of the TNFR1 level in ascite cells

  9. Following memory deficit induced by sepsis, memory is preserved in the absence of TNFR1.

  10. we identified P55 (show IL2RA Proteins)-induced goblet and Paneth cell dysfunction as a crucial mechanism for TNF (show TNF Proteins)-induced systemic and lethal inflammation.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. Retinal ischemia results in increased expression of TNF-alpha (show TNF Proteins) and its receptors (TNF-R1 and TNF-R2 (show TNFRSF1B Proteins)).

Cow (Bovine) Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. These results suggest that TNF-alpha (show TNF Proteins) sources include immune cells, as well as large and small luteal cells, and that TNF-RI and TNF-RII (show TNFRSF1B Proteins) are present in the luteal cells of the bovine corpus luteum.

  2. The expression and cellular localization of tumor necrosis factor-alpha (TNF (show TNF Proteins)) and its receptors (TNFRI and TNFRII (show TNFRSF1B Proteins)) mRNAs and proteins, were determined.

  3. The upregulation of TNFRI mRNA expression by IFNG (show IFNG Proteins) suggests that TNF (show TNF Proteins) and IFNG (show IFNG Proteins) synergistically affect the death of luteal endothelial cells resulting in acute luteolysis

  4. TNF (show TNF Proteins) binding induces release of AIP1 (DAB2IP (show DAB2IP Proteins)) from TNFR1, resulting in cytoplasmic translocation and concomitant formation of an intracellular signaling complex comprised of TRADD (show TRADD Proteins), RIP1 (show RALBP1 Proteins), TRAF2 (show TRAF2 Proteins), and AIPl.

Zebrafish Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) interaction partners

  1. Targeted gene knockdown of TNFRSF1B (show TNFRSF1B Proteins) in zebrafish embryos results in the induction of a caspase-8 (show CASP8 Proteins), caspase-2 (show CASP2 Proteins) and P53 (show TP53 Proteins)-dependent apoptotic program in endothelial cells that bypasses caspase-3 (show CASP3 Proteins).

TNFRSF1A Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.

Alternative names and synonyms associated with TNFRSF1A

  • tumor necrosis factor receptor superfamily, member 1A (tnfrsf1a)
  • tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A)
  • tumor necrosis factor receptor superfamily, member 1a (Tnfrsf1a)
  • tumor necrosis factor receptor superfamily, member 1A (Tnfrsf1a)
  • tumor necrosis factor receptor superfamily, member 1a (tnfrsf1a)
  • CD120a protein
  • FPF protein
  • MS5 protein
  • p55 protein
  • p55-R protein
  • p60 protein
  • TBP1 protein
  • TNF-alphaR1 protein
  • TNF-R protein
  • TNF-R-I protein
  • TNF-R1 protein
  • TNF-R55 protein
  • TNFalpha-R1 protein
  • TNFAR protein
  • Tnfr-2 protein
  • Tnfr1 protein
  • TNFR1-d2 protein
  • TNFR55 protein
  • TNFR60 protein
  • TNFR I protein
  • TNFRI protein
  • TNFRp55 protein
  • TNFRSF1A protein
  • wu:fj65b10 protein
  • xtnfr1 protein
  • zgc:85914 protein

Protein level used designations for TNFRSF1A

tumor necrosis factor receptor 1 , tumor necrosis factor receptor p60 , tumor necrosis factor receptor superfamily member 1A , tumor necrosis factor type I , tumor necrosis factor receptor superfamily, member 1A , tumor necrosis factor receptor superfamily member 1A-like , TNF-R1 , TNF-RI , TNFR-I , tumor necrosis factor binding protein 1 , tumor necrosis factor receptor 1A isoform beta , tumor necrosis factor receptor type 1 , tumor necrosis factor-alpha receptor , TNF receptor alpha chain , TNF-alpha-R1 , p60 , tumor necrosis factor receptor type I , p55 , p55 TNF receptor , TNF Receptor 1 (TR1) , TNFR1

GENE ID SPECIES
100137626 Xenopus laevis
100144930 Xenopus (Silurana) tropicalis
403634 Canis lupus familiaris
466934 Pan troglodytes
493957 Felis catus
722033 Macaca mulatta
100059548 Equus caballus
100135698 Ovis aries
100397418 Callithrix jacchus
7132 Homo sapiens
21937 Mus musculus
25625 Rattus norvegicus
397020 Sus scrofa
282527 Bos taurus
418325 Gallus gallus
100713890 Cavia porcellus
406471 Danio rerio
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