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anti-Zebrafish (Danio rerio) C-MYC antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended C-MYC Antibody (supplied by: Log in to see )

Antigen
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibodies
  • AU016757
  • bHLHe39
  • c-myc
  • c-Myc
  • C-MYC
  • cmyc
  • CMYC
  • CMyc
  • LOC100136746
  • mMyc
  • MRTL
  • MYC
  • Myc2
  • MYCC
  • Niard
  • Nird
  • RNCMYC
  • zc-myc
Reactivity
Human, Mouse (Murine), Zebrafish (Danio rerio)
638
188
151
10
9
6
5
5
4
3
3
3
3
3
2
1
1
1
1
Host
Rabbit
425
202
16
13
8
1
Clonality
Polyclonal
Conjugate
This C-MYC antibody is un-conjugated
40
32
28
15
14
12
4
4
4
4
4
4
4
4
4
3
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
428
230
199
114
104
91
71
44
41
36
22
11
10
9
7
6
4
4
2
2
2
Supplier
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Catalog No. ABIN357365
$ 401.50
Plus shipping costs $45.00

Top referenced anti-C-MYC antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-C-MYC Antibodies

Application / Reactivity Zebrafish (Danio rerio) Mouse (Murine) Human
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 1 Antibodies 21 Antibodies
Western Blotting (WB) 1 Antibodies 122 Antibodies
Chromatin Immunoprecipitation (ChIP) 3 Antibodies 4 Antibodies
ELISA 41 Antibodies
Immunocytochemistry (ICC) 14 Antibodies
Immunofluorescence (IF) 36 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 79 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunoprecipitation (IP) 15 Antibodies
Dot Blot (DB) 36 Antibodies
Electrophoretic Mobility-Shift Assay (EMSA) 2 Antibodies

General

Antigen V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibodies
Reactivity Human, Mouse (Murine), Zebrafish (Danio rerio)
(638), (188), (151), (10), (9), (6), (5), (5), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1)
Host Rabbit
(425), (202), (16), (13), (8), (1)
Clonality
Polyclonal
Conjugate This C-MYC antibody is un-conjugated
(40), (32), (28), (15), (14), (12), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(428), (230), (199), (114), (104), (91), (71), (44), (41), (36), (22), (11), (10), (9), (7), (6), (4), (4), (2), (2), (2)
Pubmed 3 references available
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Product Details anti-C-MYC Antibody

Target Details C-MYC Application Details Handling References for anti-C-MYC Antibody (ABIN357365) Images
Specificity This antibody detects MYC.
Purification Protein A column, followed by peptide affinity purification
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T58 of human MYC.
Isotype Ig

Target Details C-MYC

Product Details anti-C-MYC Antibody Application Details Handling References for anti-C-MYC Antibody (ABIN357365) Images back to top
Antigen
Alternative Name C-Myc (MYC Antibody Abstract)
Background MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64
Molecular Weight 48804 Da
Gene ID 4609, 9606
UniProt P01106
Research Area Transcription Factors, Cancer, Cell Cycle
Pathways p53 Signaling, Cell Division Cycle

Application Details

Product Details anti-C-MYC Antibody Target Details C-MYC Handling References for anti-C-MYC Antibody (ABIN357365) Images back to top
Application Notes ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-C-MYC Antibody Target Details C-MYC Application Details References for anti-C-MYC Antibody (ABIN357365) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

References for anti-C-MYC Antibody (ABIN357365)

Product Details anti-C-MYC Antibody Target Details C-MYC Application Details Handling Images back to top
Background publications

Lima, Bousquet, Gomez-Brouchet, de Paiva, Amstalden, Soares, Dastugue, Vassallo, Brousset: "Primary diffuse large B-cell lymphoma of bone displays preferential rearrangements of the c-MYC or BCL2 gene." in: American journal of clinical pathology, Vol. 129, Issue 5, pp. 723-6, 2008

Ida, Ogata, Okumura, Taguchi: "Changes in the gene expression of C-myc and CD38 in HL-60 cells during differentiation induced by nicotinic acid-related compounds." in: Bioscience, biotechnology, and biochemistry, Vol. 72, Issue 3, pp. 868-71, 2008

Iijima, Teraoka, Date, Tsukada: "DNA-activated protein kinase in Raji Burkitt's lymphoma cells. Phosphorylation of c-Myc oncoprotein." in: European journal of biochemistry / FEBS, Vol. 206, Issue 2, pp. 595-603, 1992

Images

Product Details anti-C-MYC Antibody Target Details C-MYC Application Details Handling References for anti-C-MYC Antibody (ABIN357365) back to top
Supplier Images
 image for anti-C-MYC antibody (V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian)) (ABIN357365) anti-V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) antibody
 image for anti-C-MYC antibody (V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian)) (ABIN357365) anti-V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) antibody (Image 2)