C-MYC antibody (Myc Proto-Oncogene protein) (pSer62) Primary Antibody
MYC
Reactivity: Human, Mouse, Rat
ELISA, ICC, IF, IHC, WB
Host: Rabbit
Polyclonal
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Catalog No. ABIN6255431
$390.77
Plus shipping costs $45.00
100 μL ABIN6255431
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- Target
- Binding Specificity
- pSer62
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugate
- This C-MYC antibody is un-conjugated
- Application
- ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
- Specificity
- Phospho-Myc (Ser62) Antibody detects endogenous levels of Myc only when phosphorylated at Serine 62
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human Myc around the phosphorylation site of Serine 62
- Isotype
- IgG
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-
- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
-
- Target
- Alternative Name
- Myc Proto-Oncogene protein (MYC Antibody Abstract)
- Background
Description: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000).
Gene: MYC
- Molecular Weight
- 50kDa
- Gene ID
- 4609
- UniProt
- P01106
- Pathways
- p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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