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Browse our anti-PDCD6IP (PDCD6IP) Antibodies

Full name:
anti-Programmed Cell Death 6 Interacting Protein Antibodies (PDCD6IP)
On are 114 Programmed Cell Death 6 Interacting Protein (PDCD6IP) Antibodies from 23 different suppliers available. Additionally we are shipping PDCD6IP Proteins (17) and PDCD6IP Kits (5) and many more products for this protein. A total of 142 PDCD6IP products are currently listed.
2310011D08Rik, AI480459, AI480591, aip1, alix, AW544830, C76364, CG12876, DAIP1, DDBDRAFT_0167145, DDBDRAFT_0185177, DDB_0167145, DDB_0185177, Dmel\\CG12876, DRIP4, Eig2, GB11744, HP95, mKIAA1375, mKIAA1743, NORI-1, PDCD6IP, RGD1561176, wu:fb70d03, wu:fy65h02, zgc:63638
list all antibodies Gene Name GeneID UniProt
PDCD6IP 69601 Q3UHC7
PDCD6IP 10015 Q8WUM4
PDCD6IP 501083  

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anti-Mouse (Murine) PDCD6IP Antibodies:

anti-Human PDCD6IP Antibodies:

anti-Rat (Rattus) PDCD6IP Antibodies:

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Top referenced anti-PDCD6IP Antibodies

  1. Human Polyclonal PDCD6IP Primary Antibody for IF, IHC - ABIN347079 : Mahul-Mellier, Hemming, Blot, Fraboulet, Sadoul: Alix, making a link between apoptosis-linked gene-2, the endosomal sorting complexes required for transport, and neuronal death in vivo. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 6 references for ABIN347079

  2. Frog Monoclonal PDCD6IP Primary Antibody for FACS, IF - ABIN2664051 : Odorizzi: The multiple personalities of Alix. in Journal of cell science 2006 (PubMed)
    Show all 5 references for ABIN2664051

  3. Human Polyclonal PDCD6IP Primary Antibody for WB - ABIN1881644 : Inuzuka, Suzuki, Kawasaki, Shibata, Wakatsuki, Maki: Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition. in BMC structural biology 2010 (PubMed)
    Show all 4 references for ABIN1881644

  4. Mouse (Murine) Monoclonal PDCD6IP Primary Antibody for IF, WB - ABIN968616 : Chen, Borinstein, Gillis, Sykes, Bogler: The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for ABIN968616

  5. Mouse (Murine) Monoclonal PDCD6IP Primary Antibody for ICFC - ABIN2664050 : Voegtli, Madrona, Wilson: The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN2664050

  6. Human Polyclonal PDCD6IP Primary Antibody for EIA, IHC (fro) - ABIN1105290 : Pasqual, Rojek, Masin, Chatton, Kunz: Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transport. in PLoS pathogens 2011 (PubMed)

  7. Human Monoclonal PDCD6IP Primary Antibody for EIA, IF - ABIN181090 : Pan, Wang, Zhou, He, Koomen, Kobayashi, Sun, Corvera, Gallick, Kuang: Involvement of the conserved adaptor protein Alix in actin cytoskeleton assembly. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against PDCD6IP Interaction Partners

Fruit Fly (Drosophila melanogaster) Programmed Cell Death 6 Interacting Protein (PDCD6IP) interaction partners

  1. We conclude that ALIX and ESCRT-III coordinately control abscission in Drosophila fGSCs and that their complex formation is required for accurate abscission timing in GSCs in vivo.

Mouse (Murine) Programmed Cell Death 6 Interacting Protein (PDCD6IP) interaction partners

  1. DAB2IP (show DAB2IP Antibodies) loss reprograms intracellular signal transduction and anti-apoptotic gene expression, which potentiates prostate cancer cell survival from androgen deprivation therapy-induced cell death.

  2. Germ cell-specific or Sertoli cell-specific deletion of Aip1 gene each led to significant defects in germ cell migration after postnatal day 4 or 5, accompanied by elevated levels of actin filaments (F-actin) in the affected cells.

  3. Cor1B, Cof1 and AIP1 work in concert through a temporally ordered pathway to induce highly efficient severing and disassembly of actin filaments.

  4. results suggest that Dab2IP plays an important role in the migration and positioning of a subpopulation of later-born (layers II-IV) neurons, likely through the regulation of Rap1 and integrin signaling.

  5. Our data reveal that AIP1, by inhibiting VEGFR2 (show KDR Antibodies)-dependent signaling in tumor niche, suppresses tumor EMT (show ITK Antibodies) switch, tumor angiogenesis, and tumor premetastatic niche formation to limit tumor growth and metastasis.

  6. AIP1 was elevated in the brain of AD Tg2576 mice. Abeta1-42 treatment induced the interaction of AIP1 and ASK1 (show MAP3K5 Antibodies), which led to dissociation of ASK1 (show MAP3K5 Antibodies) and 14-3-3 (show YWHAQ Antibodies).

  7. site-specific methylation of mDab2ip gene during cerebellar development may play a role in inclusion of exon 5, resulting in a Dab2ip (show DAB2IP Antibodies) transcript variant that encodes a full pleckstrin (show PLEK Antibodies) homology (PH) domain.

  8. ATG12 (show ATG12 Antibodies)-ATG3 (show ATG3 Antibodies) interacts with Alix to promote basal autophagic flux and late endosome function.

  9. Study showed that DAB2IP (show DAB2IP Antibodies) can be functionally inactivated by physical interaction with mutant p53 (show TP53 Antibodies) proteins with implications for the response of cancer cells to inflammatory cytokines.

  10. DAB2IP (show DAB2IP Antibodies) is a unique intrinsic androgen receptor (show AR Antibodies) modulator in normal cells, and likely can be further developed into a therapeutic agent for rpostate cancer.

Xenopus laevis Programmed Cell Death 6 Interacting Protein (PDCD6IP) interaction partners

  1. These findings establish that Xp95/Alix is phosphorylated within the proline-rich domain during M-phase induction, and indicate that the phosphorylation may both positively and negatively modulate their interaction with partner proteins.

Human Programmed Cell Death 6 Interacting Protein (PDCD6IP) interaction partners

  1. Identify positive correlations between WDR1 (show WDR1 Antibodies) and CLNK (show CLNK Antibodies) gene polymorphisms in Chinese-Tibetan gout populations.

  2. These findings indicate that Alix binds to Ago2 (show EIF2C2 Antibodies) and miRNAs, suggesting that it plays a key role in miRNA enrichment during extracellular vesicles biogenesis.

  3. The authors find that HIV-1 nucleocapsid mimics the PDZ (show INADL Antibodies) domains of syntenin (show SDCBP Antibodies), a membrane-binding adaptor involved in cell-to-cell contact/communication, to capture the Bro1 (show HMGCR Antibodies) domain of ALIX, which is an ESCRTs recruiting cellular adaptor.

  4. We found that ARRDC3 is required for ALIX ubiquitination induced by activation of PAR1 (show MARK2 Antibodies)

  5. phosphorylation of the intramolecular interaction site in the PRD (show PRD Antibodies) is one of the major mechanisms that activates the ESCRT function of ALIX

  6. homologous domain of human Bro1 (show HMGCR Antibodies) domain-containing proteins, Alix and Brox, binds CHMP4B (show CHMP4A Antibodies) but not STAM2 (show STAM2 Antibodies), despite their high structural similarity

  7. Accordingly, ALIX depletion leads to furrow regression in cells with chromosome bridges, a phenotype associated with abscission checkpoint signaling failure.

  8. Findings indicate that the PDCD6IP 15bp insertion/deletion polymorphism decreases the risk of breast neoplasm in an Iranian population.

  9. The serum lever of Alzheimer's disease were decrease and the expression of ALIX strongly correlated with the Mini-Mental State Examination scores of the AD patients

  10. our findings identify heparanase (show HPSE Antibodies) as a modulator of the syndecan (show SDC1 Antibodies)-syntenin (show SDCBP Antibodies)-ALIX pathway, fostering endosomal membrane budding and the biogenesis of exosomes by trimming the heparan sulfate chains on syndecans

PDCD6IP Antigen Profile

Antigen Summary

This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PDCD6IP

  • ALG-2 interacting protein X (ALiX) antibody
  • ALG-2 interacting protein X (alxA) antibody
  • programmed cell death 6 interacting protein (pdcd6ip) antibody
  • programmed cell death 6 interacting protein (PDCD6IP) antibody
  • Programmed cell death 6 interacting protein (Bm1_48390) antibody
  • disabled 2 interacting protein (Dab2ip) antibody
  • programmed cell death 6 interacting protein (Pdcd6ip) antibody
  • WD repeat domain 1 (WDR1) antibody
  • 2310011D08Rik antibody
  • AI480459 antibody
  • AI480591 antibody
  • aip1 antibody
  • alix antibody
  • AW544830 antibody
  • C76364 antibody
  • CG12876 antibody
  • DAIP1 antibody
  • DDBDRAFT_0167145 antibody
  • DDBDRAFT_0185177 antibody
  • DDB_0167145 antibody
  • DDB_0185177 antibody
  • Dmel\\CG12876 antibody
  • DRIP4 antibody
  • Eig2 antibody
  • GB11744 antibody
  • HP95 antibody
  • mKIAA1375 antibody
  • mKIAA1743 antibody
  • NORI-1 antibody
  • PDCD6IP antibody
  • RGD1561176 antibody
  • wu:fb70d03 antibody
  • wu:fy65h02 antibody
  • zgc:63638 antibody

Protein level used designations for PDCD6IP

ALG-2 interacting protein 1 , ALiX-PA , CG12876-PA , programmed cell death 6-interacting protein , programmed cell death 6 interacting protein , Programmed cell death 6 interacting protein , ASK-interacting protein 1 , ASK1-interacting protein 1 , DAB2-interacting protein , DOC-2/DAB-2 interactive protein , disabled 2 interacting protein long form , disabled homolog 2 interacting protein , disabled homolog 2-interacting protein , putative signal tranduction protein Xp95 , signal transduction protein Xp95 , ALG-2-interacting protein X , PDCD6-interacting protein , apoptosis-linked gene 2-interacting protein X , dopamine receptor interacting protein 4 , ALG-2-interacting protein 1 , Alg2-interacting protein 1 , Alg2-interacting protein X , E2f1-inducible protein , ALG-2 interacting protein X , WD repeat-containing protein 1 , actin-interacting protein 1

43330 Drosophila melanogaster
412662 Apis mellifera
8620152 Dictyostelium discoideum AX4
406669 Danio rerio
420725 Gallus gallus
477015 Canis lupus familiaris
496474 Xenopus (Silurana) tropicalis
6104563 Brugia malayi
100546453 Meleagris gallopavo
69601 Mus musculus
398095 Xenopus laevis
10015 Homo sapiens
18571 Mus musculus
501083 Rattus norvegicus
9948 Homo sapiens
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