anti-Mouse (Murine) TNFRSF10B antibody for Neutralization

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b-b
  • tnfrsf10b
Epitope
AA 53-177
43
31
14
12
10
10
10
9
8
8
8
5
5
5
5
5
4
4
4
4
4
3
3
3
3
3
2
2
1
1
1
1
1
1
Reactivity
Mouse (Murine)
340
78
27
1
1
1
1
1
Host
Goat
183
182
11
6
6
2
Clonality
Polyclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
25
21
16
8
6
6
5
5
5
5
5
5
5
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
196
178
73
52
39
32
27
26
15
13
13
5
4
4
3
3
2
1
Supplier
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Catalog No. ABIN4900408
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5634461 CyTOF FACS Neut WB Goat IgG AA 53-177 Log in to see Polyclonal

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Epitope AA 53-177
(43), (31), (14), (12), (10), (10), (10), (9), (8), (8), (8), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(340), (78), (27), (1), (1), (1), (1), (1)
Host Goat
(183), (182), (11), (6), (6), (2)
Clonality
Polyclonal
Conjugate This TNFRSF10B antibody is un-conjugated
(25), (21), (16), (8), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
(196), (178), (73), (52), (39), (32), (27), (26), (15), (13), (13), (5), (4), (4), (3), (3), (2), (1)
Pubmed 3 references available
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B antibody (ABIN4900408) Images
Specificity Detects mouse TRAIL R2 in direct ELISAs and Western blots. In direct ELISAs, less than 5 % cross-reactivity with recombinant human (rh) TRAIL R2 is observed.
Purification Antigen Affinity-purified
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse TRAIL R2/TNFRSF10B, Asn53-Ser177, Accession # Q6GSD9
Isotype IgG

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling References for anti-TNFRSF10B antibody (ABIN4900408) Images back to top
Antigen
Alternative Name TRAIL R2/TNFRSF10B (TNFRSF10B Antibody Abstract)
Background Alternative Names: CD262, CD262 antigen, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAILR2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9
Gene ID 8795
UniProt Q6GSD9
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling References for anti-TNFRSF10B antibody (ABIN4900408) Images back to top
Application Notes Western Blot 0.1 μg/mL
Flow Cytometry 0.25 μg/10^6 cells
Neutralization 0.4-1.2 μg/mL
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details References for anti-TNFRSF10B antibody (ABIN4900408) Images back to top
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-TNFRSF10B antibody (ABIN4900408)

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling Images back to top
Product cited in:

Shekhar, Miles, Gupte, Taylor, Tascone, Walkley, Hawkins: "IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα." in: Oncotarget, Vol. 7, Issue 23, pp. 33866-86, 2016 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Lundqvist, Yokoyama, Smith, Berg, Childs: "Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells." in: Blood, Vol. 113, Issue 24, pp. 6120-7, 2009 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Park, Wu, Choi, Najafi, Emami, Safa: "P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5." in: Biochemical pharmacology, Vol. 72, Issue 3, pp. 293-307, 2006 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Images

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B antibody (ABIN4900408) back to top
Supplier Images
Neutralization (Neut) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 53-177) antibody (ABIN4900408) Cytotoxicity Induced by TRAIL/TNFSF10 and Neutralization by Mouse TRAIL R2/TNFRSF10B ...
Neutralization (Neut) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 53-177) antibody (ABIN4900408) Cytotoxicity Induced by TRAIL/TNFSF10 and Neutralization by Mouse TRAIL R2/TNFRSF10B ...