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Loss of p27 (show PAK2 Antibodies) associated with risk for endometrial carcinoma arising in the setting of obesity.
p53 (show TP53 Antibodies) immunopositivity was more frequent in SCC (show CYP11A1 Antibodies) (65%) than in VC (23%) (P=0.001). VC had lower p53 (show TP53 Antibodies) as compared with well-differentiated SCC (show CYP11A1 Antibodies) and SCC (show CYP11A1 Antibodies) without lymph node metastasis. No significant difference was seen in pRb (show RB1 Antibodies), p16 (show CDKN2A Antibodies), and p27 (show PAK2 Antibodies) expression
The PSMD9 intronic SNPs rs74421874 (IVS3+nt460 G>A) and rs3825172 (IVS3+nt437 C>T) remain significantly associated with insomnia only when taking into account anxiety -and not depression- as covariate.
Studies have found significant associations of the treatment response with the 26S proteasome non-ATPase subunit (show PSMD14 Antibodies) 9 (show ATP5G1 Antibodies) (PSMD9), proteasome alpha type 7 (show PSMA7 Antibodies) subunit (PSMA7 (show PSMA7 Antibodies)) and PSMD13 (show PSMD13 Antibodies) genes.
recurrence rate of p27 (show PAK2 Antibodies) and/or PTEN (show PTEN Antibodies)-negative patients was higher than that of the positive ones,that should be followed up closely after treatment
The present study provided the first evidences that miR (show MLXIP Antibodies)-1470 mediated lapatinib induced p27 (show PAK2 Antibodies) upregulation by targeting c-jun (show JUN Antibodies).
Staining intensities of cell cycle inhibitors p27 (show PAK2 Antibodies) and p57 (show CDKN1C Antibodies) significantly increased in all parts of preeclamptic placentas compared to control
PSMD9 expression predicts radiotherapy response in breast cancer.
Expression of Hath1 (show ATOH1 Antibodies), Muc2 (show MUC2 Antibodies), cyclin D1 (show CCND1 Antibodies) and p27 (show PAK2 Antibodies) in the xenograft tumors was also detected.
Describe PSMD9 gene SNPs in linkage to generalized anxiety disorder in type 2 diabetic families.
These results therefore suggest that proteasomes, particularly p27 (show CDKN1B Antibodies) subunit, are directly involved in the regulation of melanin biosynthesis in mouse melanoma cells.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
, 26S proteasome non-ATPase regulatory subunit 9
, proteasome 26S non-ATPase subunit 9
, 26S proteasome regulatory subunit p27
, PDZ domain-containing protein
, homolog of rat Bridge 1
, proteasome 26S non-ATPase regulatory subunit 9
, transactivating protein Bridge-1