AXL Protein (AA 26-449) (His tag)
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- Target See all AXL Proteins
- AXL (AXL Receptor tyrosine Kinase (AXL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-449
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This AXL protein is labelled with His tag.
- Sequence
- AA 26-449
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.6 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product AXL Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- AXL (AXL Receptor tyrosine Kinase (AXL))
- Alternative Name
- Axl (AXL Products)
- Synonyms
- JTK11 Protein, UFO Protein, AI323647 Protein, Ark Protein, Tyro7 Protein, Ufo Protein, AXL receptor tyrosine kinase Protein, Axl receptor tyrosine kinase Protein, AXL Protein, Axl Protein
- Background
- AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. AXL is highly expressed in metastatic colon tumors. AXL is activated by GAS6-binding and subsequent autophosphorylation. AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.
- Molecular Weight
- 46.6 kDa
- Pathways
- RTK Signaling, Cellular Response to Molecule of Bacterial Origin
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