IL5RA Protein (AA 21-335) (His tag)
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- Target See all IL5RA Proteins
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-335
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL5RA protein is labelled with His tag.
- Sequence
- AA 21-335
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.7 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >85 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL5RA Protein
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Interleukin 5 Receptor, alpha (IL5RA) (AA 21-335) protein (His-Avi Tag,Biotin)
IL5RA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 Receptor, alpha (IL5RA) (AA 18-339) protein (His tag)IL5RA Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 Receptor, alpha (IL5RA) (AA 21-335) protein (Fc Tag)IL5RA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 Receptor, alpha (IL5RA) (AA 21-335) protein (His-Avi Tag)IL5RA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 Receptor, alpha (IL5RA) (Active) protein (His tag)IL5RA Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 5 Receptor, alpha (IL5RA) protein (His tag)IL5RA Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 5 Receptor, alpha (IL5RA) (Active) protein (His tag)IL5RA Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
- Alternative Name
- IL-5 R alpha (IL5RA Products)
- Synonyms
- MGC86517 Protein, IL5RA Protein, il5r Protein, cdw125 Protein, hsil5r3 Protein, gpIL-5ra Protein, CD125 Protein, CDw125 Protein, HSIL5R3 Protein, IL5R Protein, Il5r Protein, interleukin 5 receptor subunit alpha L homeolog Protein, interleukin 5 receptor subunit alpha Protein, interleukin 5 receptor, alpha Protein, il5ra.L Protein, IL5RA Protein, il5ra Protein, Il5ra Protein
- Background
- Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125,which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.
- Molecular Weight
- 37.7 kDa
- NCBI Accession
- NP_000555
- Pathways
- JAK-STAT Signaling
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