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2B4 Protein (Fc Tag)

CD244 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB, ELISA Active
Catalog No. ABIN2566941
  • Target See all 2B4 (CD244) Proteins
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 15
    • 4
    • 3
    Human
    Source
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This 2B4 protein is labelled with Fc Tag.
    Application
    Western Blotting (WB), ELISA
    Characteristics

    Measured by its binding ability in a functional ELISA. Immobilized human CD48 at 10 μg/mL (100 μL/well ) can bind rh CD244 / 2B4 Fc Chimera with a linear range of 0. 01 - 0. 5 μg/mL.

    Fusion tag: C-Fc Tag

    Purity
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product CD244 Protein
  • Application Notes
    This recombinant protein can be used for WB, ELISA. For research use only.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM tris, 100 mM glycine, pH 7.5
    Storage
    -80 °C,-20 °C
    Storage Comment
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    Alternative Name
    SLAMF 4 (CD244 Products)
    Synonyms
    CD244 Protein, 2B4 Protein, NAIL Protein, NKR2B4 Protein, Nmrk Protein, SLAMF4 Protein, C9.1 Protein, F730046O15Rik Protein, Ly90 Protein, CD244 molecule Protein, CD244 natural killer cell receptor 2B4 Protein, CD244 Protein, Cd244 Protein
    Background
    Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
    Molecular Weight
    48.9 kDa
    Gene ID
    51744
    NCBI Accession
    NP_057466
    UniProt
    Q9BZW8
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