2B4 Protein (Fc Tag)
-
- Target See all 2B4 (CD244) Proteins
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This 2B4 protein is labelled with Fc Tag.
- Application
- Western Blotting (WB), ELISA
- Characteristics
-
Measured by its binding ability in a functional ELISA. Immobilized human CD48 at 10 μg/mL (100 μL/well ) can bind rh CD244 / 2B4 Fc Chimera with a linear range of 0. 01 - 0. 5 μg/mL.
Fusion tag: C-Fc Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Top Product
- Discover our top product CD244 Protein
-
-
- Application Notes
- This recombinant protein can be used for WB, ELISA. For research use only.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- 50 mM tris, 100 mM glycine, pH 7.5
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
-
- Target
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
- Alternative Name
- SLAMF 4 (CD244 Products)
- Synonyms
- CD244 Protein, 2B4 Protein, NAIL Protein, NKR2B4 Protein, Nmrk Protein, SLAMF4 Protein, C9.1 Protein, F730046O15Rik Protein, Ly90 Protein, CD244 molecule Protein, CD244 natural killer cell receptor 2B4 Protein, CD244 Protein, Cd244 Protein
- Background
- Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
- Molecular Weight
- 48.9 kDa
- Gene ID
- 51744
- NCBI Accession
- NP_057466
- UniProt
- Q9BZW8
-