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Thymic Stromal Lymphopoietin Protein (TSLP) (Transcript Variant 1)

TSLP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734446
  • Target See all Thymic Stromal Lymphopoietin (TSLP) Proteins
    Thymic Stromal Lymphopoietin (TSLP)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 23
    • 10
    • 5
    • 3
    Human
    Source
    • 17
    • 15
    • 4
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TSLP (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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    Discover our top product TSLP Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handling Advice
    Resuspend the protein in the desired concentration in proper buffer
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Thymic Stromal Lymphopoietin (TSLP)
    Alternative Name
    Tslp (TSLP Products)
    Synonyms
    TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
    Background
    This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
    Molecular Weight
    15 kDa
    NCBI Accession
    NP_149024
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