Browse our anti-SURF1 (SURF1) Antibodies

On www.antibodies-online.com are 31 Surfeit 1 (SURF1) Antibodies from 14 different suppliers available. Additionally we are shipping SURF1 Proteins (10) and SURF1 Kits (1) and many more products for this protein. A total of 48 SURF1 products are currently listed.
Synonyms:
0610010F23Rik, Ab1-205, BcDNA:GH23574, CG9943, Dmel\\CG9943, GB14201, im:6898613, Surf-1, SURF1, SURFEIT 1, zgc:158646
list all antibodies Gene Name GeneID UniProt
SURF1 6834 Q15526
SURF1 64463 Q9QXU2
SURF1 20930 P09925

Most Popular Reactivities for anti-SURF1 (SURF1) Antibodies

anti-Human SURF1 Antibodies:

anti-Rat (Rattus) SURF1 Antibodies:

anti-Mouse (Murine) SURF1 Antibodies:

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More Antibodies against SURF1 Interaction Partners

Human Surfeit 1 (SURF1) interaction partners

  1. Mutations in the SURF1 gene are a cause of Charcot-Marie-Tooth disease.

  2. This study suggested that hypertrophic olivary degeneration on magnetic resonance imaging in mitochondrial syndromes associated with POLG (show POLG Antibodies) and SURF1 mutations.

  3. sequenced the SURF1 gene and identified two heterozygous mutations; c.49+1 G>T and c.752_753del in Case 1, and homozygous c.743 C>A in Case 2

  4. Study identified 21 patients with clinical features of Leigh syndrome who are either homozygous or compound heterozygous for SURF1 mutations.

  5. Analysis of fibroblast cell lines from 9 patients with SURF1 mutations revealed a 70% decrease of the COX (show COX8A Antibodies) complex content to be associated with 32-54% upregulation of respiratory chain complexes I, III and V and accumulation of Cox5a (show COX5A Antibodies) subunit.

  6. Analysis of mutations in the SURF1 homolog Shy1 revealed Coa4, a new member of the cytochrome oxidase assembly factor family.

  7. Three novel mutations of the SURF-1 gene were identified in Japanese patients with cytochrome c (show CYCS Antibodies) oxidase deficiency; loss of function of the SURF-1 protein; cytochrome c (show CYCS Antibodies) oxidase activity was decreased to less than 20% of the control mean.

  8. new missense mutation of 574C>T in the SURF1 gene in Leigh's syndrome

  9. Two novel pathogenic SURF1 mutations have been identified in a patient with Leigh syndrome.

  10. Mutations in the nuclear SURF1 gene are specifically associated with cytochrome c (show CYCS Antibodies) oxidase (COX (show COX8A Antibodies))-deficient Leigh syndrome. MR imaging abnormalities in three children with this condition involved the brain.

Mouse (Murine) Surfeit 1 (SURF1) interaction partners

  1. These findings suggest that Surf1 deficiency-induced metabolic alterations may have positive effects on brain function.

  2. The expression of peroxisome proliferator-activated receptor gamma-coactivator 1-alpha (PGC-1alpha (show PPARGC1A Antibodies)) mRNA and protein was up-regulated in white adipose tissue from Surf1-/- mice, and the expression of PGC-1alpha (show PPARGC1A Antibodies) target genes

  3. Compared to wild type (WT) preparations Surf1 knockout preparations had a higher baseline respiratory frequency and abnormal responses to hypoxia and hypercapnia that involved both respiratory frequency and motor nerve discharge pattern.

  4. murine Surf1 protein (Surf1p) has a function specifically related to cytochrome c (show CYCS Antibodies) oxidase

  5. Prolonged lifespan and complete protection from Ca(2 (show CA2 Antibodies)+)-dependent neurotoxicity induced by kainic acid in Surf-1 knockout mice.

SURF1 Antigen Profile

Antigen Summary

This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.

Alternative names and synonyms associated with SURF1

  • Surfeit 1 (Surf1) antibody
  • surfeit 1 (Surf1) antibody
  • surfeit 1 (SURF1) antibody
  • surfeit 1 (surf1) antibody
  • surfeit gene 1 (Surf1) antibody
  • Surfeit locus 1 cytochrome c oxidase biogenesis protein (SURF1) antibody
  • 0610010F23Rik antibody
  • Ab1-205 antibody
  • BcDNA:GH23574 antibody
  • CG9943 antibody
  • Dmel\\CG9943 antibody
  • GB14201 antibody
  • im:6898613 antibody
  • Surf-1 antibody
  • SURF1 antibody
  • SURFEIT 1 antibody
  • zgc:158646 antibody

Protein level used designations for anti-Surfeit 1 (SURF1) Antibodies

CG9943-PA , Surf1-PA , surfeit 1 , surfeit locus protein 1 , surfeit protein

GENE ID SPECIES
44498 Drosophila melanogaster
413781 Apis mellifera
480681 Canis lupus familiaris
557970 Danio rerio
693110 Bombyx mori
6834 Homo sapiens
64463 Rattus norvegicus
417157 Gallus gallus
20930 Mus musculus
821310 Arabidopsis thaliana
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