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Human NCR3 Protein expressed in Human Cells - ABIN2002934
Pende, Parolini, Pessino, Sivori, Augugliaro, Morelli, Marcenaro, Accame, Malaspina, Biassoni, Bottino, Moretta, Moretta: Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells. in The Journal of experimental medicine 1999
Show all 4 references for ABIN2002934
Human NCR3 Protein expressed in HEK-293 Cells - ABIN2181532
Vitale, Della Chiesa, Carlomagno, Pende, Aricò, Moretta, Moretta: NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor. in Blood 2005
Show all 3 references for ABIN2181532
Age and CMV serostatus influence the expression of NKp30, NKp46 (show NCR1 Proteins) and DNAM-1 (show CD226 Proteins) activating receptors on resting and IL-2 (show IL2 Proteins) activated natural killer cells.
NKp30-B7-H6 (show NCR3LG1 Proteins) interaction is a novel cell contact mechanism that mediates activation of Group 2 innate lymphoid cells and identifies a potential target for the development of novel therapeutics for atopic dermatitis and other atopic diseases.
Our results suggest that NKP30-B7-H6 (show NCR3LG1 Proteins) interaction can aggravate hepatocyte damage, probably through up-regulation of IL-32 (show IL32 Proteins) expression in hepatitis B virus-related acute-on-chronic liver failure
the interaction between NKp30 and B7-H6 (show NCR3LG1 Proteins) may contribute to the fate of neuroblastoma (show ARHGEF16 Proteins) patients
Suggest role for NKp30 isoforms in influencing liver damage and ensuing fibrosis in chronic hepatitis C infection.
show that in addition to NKG2D (show KLRK1 Proteins), human CEACAM1 (show CEACAM1 Proteins) can inhibit NK-cell activation via NKp30 or 2B4 (show CD244 Proteins)
Up-regulation of DNAM-1 (show CD226 Proteins) and NKp30, associated with improvement of NK cells activation after long-term culture of mononuclear cells from patients with ovarian neoplasms.
Tumor-released Galectin-3 (show LGALS3 Proteins), a soluble inhibitory ligand of human NKp30, plays an important role in tumor escape from NK cell attack.
Allogeneic and xenogeneic anti-tumor effect of callithrix jacchus natural killer cells is dependent on NKp30 and B7-H6 (show NCR3LG1 Proteins) interaction.
NKp30 was required for natural killer cell-fungal conjugate formation, phosphatidylinositol 3-kinase (PI3K (show PIK3CA Proteins)) signaling, and perforin (show PRF1 Proteins) release.
phenotypic, molecular, and functional characterization for triggering molecules (NKp46 (show NCR1 Proteins), NKp30 NKp80 (show KLRF1 Proteins), and NKG2D (show KLRK1 Proteins); in this AIDS-resistant species, relevant differences to human NK cells involve NKp80 (show KLRF1 Proteins) and particularly NKp30
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
natural cytotoxicity triggering receptor 3
, activating NK-A1 receptor
, activating natural killer receptor p30
, lymphocyte antigen 117
, natural killer cell p30-related protein
, NK receptor 1c7
, natural killer cell p30-related