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anti-Mouse (Murine) TSC2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended TSC2 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 2 (TSC2) Antibodies
  • fc16b02
  • LAM
  • Nafld
  • Rc
  • Tcs2
  • TSC2
  • TSC4
  • tuberin
  • wu:fc16b02
Reactivity
Human, Mouse (Murine), Rat (Rattus)
505
373
206
6
Host
Rabbit
679
24
Clonality
Polyclonal
Conjugate
This TSC2 antibody is un-conjugated
51
51
51
42
42
42
9
9
9
9
9
9
9
9
9
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
384
291
215
132
101
58
48
9
7
6
4
2
1
Supplier
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Catalog No. ABIN498904
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.33769524 ABIN498905 IHC (p) Rabbit Log in to see Polyclonal
0.33769524 ABIN498813 IHC (p) Rabbit pSer939 Log in to see Polyclonal
0.33769524 ABIN498814 IHC (p) Rabbit pThr1462 Log in to see Polyclonal
0.33769524 ABIN712121 IF (p) IHC (p) WB Rabbit IgG pSer1798 Log in to see Polyclonal
0.0009015372 ABIN272089 IHC (p) WB Rabbit Log in to see Polyclonal
0.0009015372 ABIN272090 IHC (p) Rabbit Log in to see Polyclonal
0.0009015372 ABIN3043498 IHC (p) WB Rabbit IgG AA 1611-1807 Log in to see Polyclonal
0.0009015372 ABIN302895 IHC (p) WB Rabbit Log in to see Polyclonal
0.0009015372 ABIN303312 IF IHC (p) WB Rabbit N-Term Log in to see Polyclonal
0.0009015372 ABIN701200 IF (p) IHC (p) Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0009015372 ABIN1740411 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
0.0009015372 ABIN701202 IHC (p) Biotin Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0009015372 ABIN701209 IHC (p) HRP Rabbit IgG AA 1600-1650 Log in to see Polyclonal
0.0009015372 ABIN1740412 ICC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
0.0009015372 ABIN746440 IHC (p) WB Biotin Rabbit IgG pThr927 Log in to see Polyclonal
0.0009015372 ABIN746650 IHC (p) Biotin Rabbit IgG pSer1254 Log in to see Polyclonal
0.0009015372 ABIN746657 IHC (p) HRP Rabbit IgG pSer1254 Log in to see Polyclonal
0.0009015372 ABIN746380 IHC (p) WB Biotin Rabbit IgG pSer1387 Log in to see Polyclonal
0.0009015372 ABIN746387 IHC (p) WB HRP Rabbit IgG pSer1387 Log in to see Polyclonal
0.0009015372 ABIN746447 IHC (p) WB HRP Rabbit IgG pThr927 Log in to see Polyclonal

Similar anti-TSC2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 202 Antibodies 97 Antibodies 70 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 64 Antibodies 45 Antibodies 40 Antibodies
Immunohistochemistry (IHC) 137 Antibodies 46 Antibodies 48 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies 2 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 101 Antibodies 101 Antibodies 101 Antibodies
Immunofluorescence (IF) 46 Antibodies

General

Antigen Tuberous Sclerosis 2 (TSC2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(505), (373), (206), (6)
Host Rabbit
(679), (24)
Clonality
Polyclonal
Conjugate This TSC2 antibody is un-conjugated
(51), (51), (51), (42), (42), (42), (9), (9), (9), (9), (9), (9), (9), (9), (9)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(384), (291), (215), (132), (101), (58), (48), (9), (7), (6), (4), (2), (1)
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Product Details anti-TSC2 Antibody

Target Details TSC2 Application Details Handling Images
Specificity This antibody detects endogenous levels of Tsc2 protein. (region surrounding Pro945)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S1254 of human TSC2.

Target Details TSC2

Product Details anti-TSC2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Tuberin / TSC2 (TSC2 Antibody Abstract)
Background TSC2 is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Mutations in TSC2 lead to tuberous sclerosis complex.Synonyms: TSC4, Tuberous sclerosis 2 protein
Molecular Weight approx. 200 kDa
Gene ID 7249
NCBI Accession NP_000539
UniProt P49815
Pathways RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-TSC2 Antibody Target Details TSC2 Handling Images back to top
Application Notes Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-TSC2 antibody (Tuberous Sclerosis 2) (ABIN498904) Immunohistochemistry (IHC) analyzes of Tsc2 antibody in paraffin-embedded huma...