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Tuberin antibody
TSC2
Reactivity: Human, Mouse, Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Tuberin Antibody
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Target
See all Tuberin (TSC2) Antibodies
Tuberin (TSC2)
(Tuberous Sclerosis 2 (TSC2))
Reactivity
All reactivities for Tuberin antibodies
Human, Mouse, Rat
Host
All hosts for Tuberin antibodies
Rabbit
Clonality
All clonalities for Tuberin antibodies
Polyclonal
Conjugate
All conjugates for Tuberin antibodies
This Tuberin antibody is un-conjugated
Application
All applications for Tuberin antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human TSC2 (NP_000539.2).
Isotype
IgG
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Discover our top product TSC2 Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Tuberin
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Target
Tuberin (TSC2)
(Tuberous Sclerosis 2 (TSC2))
Alternative Name
TSC2 (TSC2 Products )
Synonyms
TSC2 antibody, fc16b02 antibody, tuberin antibody, wu:fc16b02 antibody, LAM antibody, TSC4 antibody, Nafld antibody, Tcs2 antibody, Rc antibody, TSC complex subunit 2 antibody, tuberin antibody, hypothetical protein antibody, tuberous sclerosis 2 antibody, TSC2 antibody, LOC5569538 antibody, tsc2 antibody, PGTG_00159 antibody, Tsc2 antibody
Background
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
7249
UniProt
P49815
Pathways
RTK Signaling , AMPK Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Cell Size , Tube Formation , Protein targeting to Nucleus
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