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|Application / Reactivity||Rat (Rattus)|
|Dot Blot (DB)||19 Antibodies|
|Immunochromatography (IC)||2 Antibodies|
|Immunocytochemistry (ICC)||2 Antibodies|
|Immunofluorescence (IF)||9 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||104 Antibodies|
|Immunohistochemistry (IHC)||48 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||2 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||40 Antibodies|
|Western Blotting (WB)||70 Antibodies|
|Antigen||Tuberous Sclerosis 2 (TSC2) Antibodies|
|Reactivity||Rat (Rattus) Alternatives|
|Conjugate||This TSC2 antibody is un-conjugated Alternatives|
Dot Blot (DB)
|3 references available|
|Supplier||Log in to see|
Product Details anti-TSC2 AntibodyTarget Details TSC2 Application Details Handling References for anti-TSC2 Antibody (ABIN1881935) Images
|Purification||This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Immunogen||This rat TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1373 of rat TSC2.|
Target Details TSC2Product Details anti-TSC2 Antibody Application Details Handling References for anti-TSC2 Antibody (ABIN1881935) Images back to top
|Alternative Name||TSC2 (TSC2 Antibody Abstract)|
Acts as a tumor suppressor, may play a role in cell cycle regulation, acute phase response, and negative regulation of cell proliferation [RGD].
Synonyms: Tsc2, Tuberin, Tuberous sclerosis 2 protein homolog
|Pathways||RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway|
Application DetailsProduct Details anti-TSC2 Antibody Target Details TSC2 Handling References for anti-TSC2 Antibody (ABIN1881935) Images back to top
|Application Notes||DB: 1:500|
|Restrictions||For Research Use only|
HandlingProduct Details anti-TSC2 Antibody Target Details TSC2 Application Details References for anti-TSC2 Antibody (ABIN1881935) Images back to top
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.|
|Precaution of Use||WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.|
References for anti-TSC2 Antibody (ABIN1881935)Product Details anti-TSC2 Antibody Target Details TSC2 Application Details Handling Images back to top
|Product cited in:||
Larson, Liu, Stevens et al.: "Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24987-98, 2010 (PubMed).
Di Nardo, Kramvis, Cho et al.: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, 2009 (PubMed).
Shiono, Kobayashi, Takahashi et al.: "The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition." in: Oncogene, Vol. 27, Issue 52, pp. 6690-7, 2008 (PubMed).
ImagesProduct Details anti-TSC2 Antibody Target Details TSC2 Application Details Handling References for anti-TSC2 Antibody (ABIN1881935) back to top